The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC COM 00287Y109 237,669 1,466,100 SH   SOLE   1,466,100 0 0
ADICET BIO INC COM 007002108 62,306 3,120,000 SH   SOLE   3,120,000 0 0
ALPHATEC HLDGS INC COM NEW 02081G201 31,459 2,735,600 SH   SOLE   2,735,600 0 0
ALPINE IMMUNE SCIENCES INC COM 02083G100 10,827 1,207,000 SH   SOLE   1,207,000 0 0
ALTIMMUNE INC COM NEW 02155H200 17,448 2,865,000 SH   SOLE   2,865,000 0 0
AN2 THERAPEUTICS INC COM 037326105 10,373 688,330 SH   SOLE   688,330 0 0
ANTHEM INC COM 036752103 196,193 399,400 SH   SOLE   399,400 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 10,670 210,000 SH   SOLE   210,000 0 0
ARCUS BIOSCIENCES INC COM 03969F109 28,783 912,000 SH   SOLE   912,000 0 0
ARGENX SE SPONSORED ADR 04016X101 55,495 176,000 SH   SOLE   176,000 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 43,920 955,000 SH   SOLE   955,000 0 0
ARVINAS INC COM 04335A105 196,200 2,915,300 SH   SOLE   2,915,300 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 4,900 500,000 SH   SOLE   500,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 245,458 3,700,000 SH   SOLE   3,700,000 0 0
AVANTOR INC COM 05352A100 191,702 5,668,300 SH   SOLE   5,668,300 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 37,771 2,045,000 SH   SOLE   2,045,000 0 0
AXSOME THERAPEUTICS INC COM 05464T104 29,428 711,000 SH   SOLE   711,000 0 0
BAUSCH HEALTH COS INC COM 071734107 38,724 1,694,700 SH   SOLE   1,694,700 0 0
BAXTER INTL INC COM 071813109 148,528 1,915,500 SH   SOLE   1,915,500 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 4,935 500,000 SH   SOLE   500,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 25,353 3,685,000 SH   SOLE   3,685,000 0 0
BIOGEN INC COM 09062X103 76,869 365,000 SH   SOLE   365,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 145,960 1,231,000 SH   SOLE   1,231,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 18,601 291,184 SH   SOLE   291,184 0 0
BOSTON SCIENTIFIC CORP COM 101137107 52,975 1,196,100 SH   SOLE   1,196,100 0 0
CAREMAX INC COM CL A 14171W103 5,642 755,329 SH   SOLE   755,329 0 0
CARIBOU BIOSCIENCES INC COM 142038108 25,879 2,819,067 SH   SOLE   2,819,067 0 0
CATALENT INC COM 148806102 86,724 782,000 SH   SOLE   782,000 0 0
CENTURY THERAPEUTICS INC COM 15673T100 10,890 865,000 SH   SOLE   865,000 0 0
CHEMOCENTRYX INC COM 16383L106 29,457 1,175,000 SH   SOLE   1,175,000 0 0
COMPASS THERAPEUTICS INC COM 20454B104 2,740 2,000,000 SH   SOLE   2,000,000 0 0
CYTEIR THERAPEUTICS INC COM 23284P103 6,975 1,850,000 SH   SOLE   1,850,000 0 0
DYNAMICS SPECIAL PURPOSE COR CLASS A COM 268010105 4,935 500,000 SH   SOLE   500,000 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 51,797 440,000 SH   SOLE   440,000 0 0
ERASCA INC COM 29479A108 8,557 995,000 SH   SOLE   995,000 0 0
ESSA PHARMA INC COM NEW 29668H708 15,203 2,460,000 SH   SOLE   2,460,000 0 0
FIELD TRIP HEALTH LTD COM 31656R102 3,988 2,976,000 SH   SOLE   2,976,000 0 0
GALAPAGOS NV SPON ADR 36315X101 13,334 215,000 SH   SOLE   215,000 0 0
GRAPHITE BIO INC COM 38870X104 3,621 710,000 SH   SOLE   710,000 0 0
GRITSTONE BIO INC COM 39868T105 2,307 560,000 SH   SOLE   560,000 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 3,964 400,000 SH   SOLE   400,000 0 0
HELIX ACQUISITION CORP COM CL A G4444C102 4,440 400,000 SH   SOLE   400,000 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 119,035 1,131,400 SH   SOLE   1,131,400 0 0
HUMANA INC COM 444859102 86,555 198,900 SH   SOLE   198,900 0 0
HYPERFINE INC COM CL A 44916K106 5,323 1,503,754 SH   SOLE   1,503,754 0 0
IDEAYA BIOSCIENCES INC COM 45166A102 30,101 2,690,000 SH   SOLE   2,690,000 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105 40,778 1,363,800 SH   SOLE   1,363,800 0 0
INSMED INC COM PAR $.01 457669307 31,832 1,354,539 SH   SOLE   1,354,539 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 28,347 390,075 SH   SOLE   390,075 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 98,046 325,000 SH   SOLE   325,000 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 100,620 6,043,219 SH   SOLE   6,043,219 0 0
IVERIC BIO INC COM 46583P102 108,981 6,475,400 SH   SOLE   6,475,400 0 0
JOHNSON & JOHNSON COM 478160104 62,739 354,000 SH   SOLE   354,000 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 58,469 3,518,000 SH   SOLE   3,518,000 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 39,792 1,095,000 SH   SOLE   1,095,000 0 0
MCKESSON CORP COM 58155Q103 58,012 189,500 SH   SOLE   189,500 0 0
MEDICUS SCIENCES ACQUISITION CL A SHS G5960S108 5,086 520,000 SH   SOLE   520,000 0 0
MEDICUS SCIENCES ACQUISITION *W EXP 02/12/202 G5960S124 25 57,770 SH   SOLE   57,770 0 0
MERCK & CO INC COM 58933Y105 194,459 2,370,000 SH   SOLE   2,370,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 114,532 1,393,000 SH   SOLE   1,393,000 0 0
NATERA INC COM 632307104 52,884 1,300,000 SH   SOLE   1,300,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 108,750 1,160,000 SH   SOLE   1,160,000 0 0
NUVATION BIO INC COM CL A 67080N101 25,537 4,855,006 SH   SOLE   4,855,006 0 0
NUVATION BIO INC *W EXP 07/07/202 67080N119 76 99,999 SH   SOLE   99,999 0 0
ONCOSEC MED INC COM 68234L306 3,387 2,945,000 SH   SOLE   2,945,000 0 0
OTONOMY INC COM 68906L105 3,240 1,349,905 SH   SOLE   1,349,905 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106 4,875 500,000 SH   SOLE   500,000 0 0
PENUMBRA INC COM 70975L107 23,102 104,000 SH   SOLE   104,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 5,815 4,405,000 SH   SOLE   4,405,000 0 0
PHATHOM PHARMACEUTICALS INC COM 71722W107 26,485 1,946,000 SH   SOLE   1,946,000 0 0
SCIENCE 37 HOLDINGS INC COM 808644108 2,301 430,000 SH   SOLE   430,000 0 0
SCYNEXIS INC COM NEW 811292200 2,127 544,043 SH   SOLE   544,043 0 0
SEAGEN INC COM 81181C104 14,405 100,000 SH   SOLE   100,000 0 0
SEASPINE HLDGS CORP COM 81255T108 24,442 2,010,000 SH   SOLE   2,010,000 0 0
SEMA4 HOLDINGS CORP COM CL A 81663L101 2,917 950,000 SH   SOLE   950,000 0 0
SENTINELONE INC CL A 81730H109 7,922 204,500 SH   SOLE   204,500 0 0
SI-BONE INC COM 825704109 22,600 1,000,000 SH   SOLE   1,000,000 0 0
SOCIAL CAP SUVRETTA HLD CRPI CLASS A ORD SHS G8253W109 1,980 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CP CLASS A ORD SHS G8253Y105 1,948 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253T106 1,978 200,000 SH   SOLE   200,000 0 0
SOCIAL CAP SUVRETTA HLDS CRP CLASS A ORD SHS G8253U103 1,950 200,000 SH   SOLE   200,000 0 0
SPDR SER TR S&P BIOTECH 78464A870 39,547 440,000 SH   SOLE   440,000 0 0
SPDR SER TR S&P BIOTECH 78464A900 296,604 3,300,000 SH Call SOLE   3,300,000 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 83,831 4,823,400 SH   SOLE   4,823,400 0 0
TANGO THERAPEUTICS INC COM 87583X109 5,465 721,000 SH   SOLE   721,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 63,107 869,000 SH   SOLE   869,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 128,986 718,946 SH   SOLE   718,946 0 0
UNITEDHEALTH GROUP INC COM 91324P102 132,388 259,600 SH   SOLE   259,600 0 0
VERTEX PHARMACEUTICALS COM 92532F100 142,385 545,600 SH   SOLE   545,600 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 20,062 780,000 SH   SOLE   780,000 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 19,230 1,040,000 SH   SOLE   1,040,000 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 146,587 3,176,999 SH   SOLE   3,176,999 0 0