The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107 18,597 1,408,901 SH   SOLE   1,408,901 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 8,461 600,523 SH   SOLE   600,523 0 0
ADAGIO THERAPEUTICS INC COM 00534A102 6,354 1,937,207 SH   SOLE   1,937,207 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 2,701 5,347,689 SH   SOLE   5,347,689 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101 37,523 1,948,214 SH   SOLE   1,948,214 0 0
ANNEXON INC COM 03589W102 12,221 3,241,628 SH   SOLE   3,241,628 0 0
APTINYX INC COM 03836N103 4,961 8,891,758 SH   SOLE   8,891,758 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108 63,930 3,000,000 SH   SOLE   3,000,000 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108 6,867 700,000 SH   SOLE   700,000 0 0
ARYA SCIENCES ACQUISITN CORP CLASS A ORD SHS G31658100 4,860 500,000 SH   SOLE   500,000 0 0
ATEA PHARMACEUTICALS INC COM 04683R106 17,648 2,485,638 SH   SOLE   2,485,638 0 0
BCLS ACQUISITION CORP COM CL A G0904B105 4,826 487,500 SH   SOLE   487,500 0 0
C4 THERAPEUTICS INC COM STK 12529R107 12,382 1,642,210 SH   SOLE   1,642,210 0 0
CARA THERAPEUTICS INC COM 140755109 24,171 2,647,473 SH   SOLE   2,647,473 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 42,999 2,305,558 SH   SOLE   2,305,558 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 105,945 8,415,000 SH   SOLE   8,415,000 0 0
EQRX INC COM 26886C107 46,917 10,003,573 SH   SOLE   10,003,573 0 0
FRAZIER LIFESCIENCES ACQU CO UNIT 12/09/2025 G3710A121 2,961 300,000 SH   SOLE   300,000 0 0
MARINUS PHARMACEUTICALS INC COM NEW 56854Q200 6,926 1,431,058 SH   SOLE   1,431,058 0 0
MERSANA THERAPEUTICS INC COM 59045L106 40,026 8,663,673 SH   SOLE   8,663,673 0 0
NAUTILUS BIOTECHNOLOGY INC COM 63909J108 5,380 2,000,000 SH   SOLE   2,000,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 23,096 1,822,883 SH   SOLE   1,822,883 0 0
NUVALENT INC COM 670703107 46,484 3,428,014 SH   SOLE   3,428,014 0 0
PANACEA ACQUISITION CORP II CL A SHS G6882C106 4,880 500,000 SH   SOLE   500,000 0 0
PHARVARIS N V COM N69605108 70,291 3,180,601 SH   SOLE   3,180,601 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 17,881 2,260,572 SH   SOLE   2,260,572 0 0
RAPID MICRO BIOSYSTEMS INC CLASS A COM 75340L104 36,269 8,434,560 SH   SOLE   8,434,560 0 0
RESEARCH ALLIANCE CORP II COM CL A 760873109 9,800 1,000,000 SH   SOLE   1,000,000 0 0
SAVARA INC COM 805111101 17,666 11,622,598 SH   SOLE   11,622,598 0 0
SOLID BIOSCIENCES INC COM 83422E105 4,882 7,929,918 SH   SOLE   7,929,918 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 118,947 4,831,307 SH   SOLE   4,831,307 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 6,031 6,264,420 SH   SOLE   6,264,420 0 0
TANGO THERAPEUTICS INC COM 87583X109 8,706 1,921,790 SH   SOLE   1,921,790 0 0
X4 PHARMACEUTICALS INC COM 98420X103 2,914 3,019,540 SH   SOLE   3,019,540 0 0
XILIO THERAPEUTICS INC COM 98422T100 8,192 2,805,413 SH   SOLE   2,805,413 0 0