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| In millions, except per share items | Dec-31-22 | Jun-30-22 | Mar-31-22 | Dec-31-21 | Sep-30-21 | Jun-30-21 | Mar-31-21 | Dec-31-20 |
| | 8-K | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-K |
| Revenues: |
| OPZELURA | | 16.6 | 12.8 | | | | | |
| MINJUVI | | 4.4 | 4.5 | 4.4 | 0.6 | | | |
| Other | | 890.4 | 716.0 | 858.5 | 812.4 | | | |
| Total revenues [+] | 926.7 | 911.4 | 733.2 | 862.9 | 813.0 | 705.7 | 604.7 | 789.5 |
| Royalties | 501.4 | | | | | | | |
| Products | 764.2 | | | | | | | |
| Revenue growth [+] | 7.4% | 29.1% | 21.3% | 9.3% | 31.0% | 2.6% | 6.4% | 36.3% |
| JAKAVI Royalty Revenues | | 2.0% | 8.0% | 9.9% | 38.6% | 23.9% | 16.5% | 33.9% |
| Cost of goods sold | 59.2 | 50.6 | 42.6 | 43.9 | 39.9 | 38.0 | 29.2 | 36.3 |
| Gross profit | 867.5 | 860.8 | 690.6 | 819.0 | 773.1 | 667.7 | 575.5 | 753.2 |
| Gross margin | 93.6% | 94.4% | 94.2% | 94.9% | 95.1% | 94.6% | 95.2% | 95.4% |
| Selling, general and administrative [+] | 272.8 | 253.3 | 209.6 | 226.2 | 190.7 | 168.9 | 153.8 | 167.0 |
| General and administrative | | | | 226.2 | | | | 167.0 |
| Research and development | | 347.2 | 353.4 | 472.8 | 334.9 | 343.5 | 306.9 | 405.9 |
| Other operating expenses | 524.6 | 2.5 | 4.7 | 7.5 | 9.1 | 9.8 | 10.5 | 12.4 |
| EBITDA [+] | | 274.3 | 139.4 | 127.3 | 253.0 | 159.9 | 118.2 | 181.0 |
| EBITDA growth | -44.9% | 71.5% | 17.9% | -29.7% | 896.7% | -35.9% | -118.3% | 62.4% |
| EBITDA margin | 7.6% | 30.1% | 19.0% | 14.7% | 31.1% | 22.7% | 19.5% | 22.9% |
| Depreciation and amortization | | 16.5 | 16.4 | 14.9 | 14.7 | 14.5 | 13.8 | 13.2 |
| EBIT [+] | 70.1 | 257.7 | 122.9 | 112.4 | 238.3 | 145.5 | 104.3 | 167.8 |
| EBIT growth | -37.6% | 77.2% | 17.8% | -33.0% | 1816.5% | -38.6% | -115.9% | 71.0% |
| EBIT margin | 7.6% | 28.3% | 16.8% | 13.0% | 29.3% | 20.6% | 17.3% | 21.3% |
| Non-recurring items [+] | | 3.3 | 6.4 | 1.7 | 2.9 | 4.6 | 5.5 | 3.6 |
| Loss on contingent liability | | 3.3 | 6.4 | 1.7 | 2.9 | 4.6 | 5.5 | 3.6 |
| Interest expense | 0.7 | 0.7 | 0.7 | 0.8 | 0.4 | 0.4 | 0.4 | 0.4 |
| Interest expense | 0.7 | 0.7 | 0.7 | 0.8 | 0.4 | 0.4 | 0.4 | 0.4 |
| Other income (expense), net [+] | 11.2 | -24.4 | -45.3 | 10.0 | -25.5 | 31.2 | -29.1 | 4.3 |
| Other | | 0.5 | 1.3 | 5.7 | 1.9 | 4.4 | -1.4 | 4.8 |
| Pre-tax income | 80.6 | 229.4 | 70.5 | 120.0 | 209.5 | 171.6 | 69.3 | 168.1 |
| Income taxes | 52.2 | 67.9 | 32.5 | -443.8 | 27.7 | 22.2 | 15.8 | 18.3 |
| Tax rate | 64.7% | 29.6% | 46.1% | | 13.2% | 12.9% | 22.8% | 10.9% |
| Net income | 28.5 | 161.4 | 38.0 | 563.9 | 181.7 | 149.5 | 53.5 | 149.9 |
| Net margin | 3.1% | 17.7% | 5.2% | 65.3% | 22.4% | 21.2% | 8.9% | 19.0% |
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| Basic EPS [+] | $0.13 | $0.73 | $0.17 | $2.56 | $0.82 | $0.68 | $0.24 | $0.69 |
| Growth | -95.0% | 7.2% | -29.5% | 272.3% | -1284.3% | -49.1% | -107.3% | 33.0% |
| Diluted EPS [+] | $0.13 | $0.72 | $0.17 | $2.54 | $0.82 | $0.67 | $0.24 | $0.69 |
| Growth | -95.0% | 7.3% | -29.4% | 269.5% | -1276.8% | -48.9% | -107.3% | 34.7% |
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| Shares outstanding (basic) [+] | 222.6 | 221.7 | 221.3 | 220.4 | 220.8 | 220.1 | 219.8 | 218.1 |
| Growth | 1.0% | 0.7% | 0.7% | 1.1% | 0.9% | 1.2% | 1.4% | 1.5% |
| Shares outstanding (diluted) [+] | 224.8 | 223.7 | 223.0 | 222.1 | 222.2 | 222.3 | 221.9 | 218.1 |
| Growth | 1.2% | 0.6% | 0.5% | 1.8% | 1.6% | 0.8% | 2.4% | 0.2% |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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