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In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
Revenues: |
PEMAZYRE Royalty Revenues | 1.2 | | | | | | | |
OPZELURA | 128.7 | 4.7 | | | | | | |
United States | 3,200.0 | 2,900.0 | 2,600.0 | | | | | |
MINJUVI | 19.7 | 4.9 | | | | | | |
Other | 45.0 | 76.7 | 66.7 | | | | | |
Total revenues [+] | 3,394.6 | 2,986.3 | 2,666.7 | 2,158.8 | 1,881.9 | 1,536.2 | 1,105.7 | 753.8 |
Royalties | | | | | | | | 74.8 |
Products | | | | | | | | 601.0 |
Contracts | | | | | | | | 77.9 |
Other | | | | | | | | 0.1 |
Revenue growth [+] | 13.7% | 12.0% | 23.5% | 14.7% | 22.5% | 38.9% | 46.7% | 47.4% |
OPZELURA | 2657.8% | | | | | | | |
United States | 10.3% | 11.5% | | | | | | |
MINJUVI | 300.3% | | | | | | | |
JAKAVI Royalty Revenues | -1.9% | 21.6% | 23.0% | 16.0% | 28.4% | | | |
Cost of goods sold | 207.0 | 151.0 | 131.3 | 114.2 | 94.1 | 79.5 | 58.2 | 27.0 |
Gross profit | 3,187.6 | 2,835.3 | 2,535.4 | 2,044.5 | 1,787.8 | 1,456.7 | 1,047.5 | 726.8 |
Gross margin | 93.9% | 94.9% | 95.1% | 94.7% | 95.0% | 94.8% | 94.7% | 96.4% |
Selling, general and administrative | 1,002.1 | 739.6 | 516.9 | 468.7 | 434.4 | 366.3 | 303.3 | 196.6 |
Research and development | 1,585.9 | 1,458.2 | 2,215.9 | 1,154.1 | 1,198.0 | 1,326.1 | 581.9 | 479.5 |
Other operating expenses | 8.0 | 37.0 | 42.8 | | | | | |
EBITDA [+] | 659.4 | 658.4 | -188.5 | 476.2 | 210.4 | -183.5 | 220.8 | 95.5 |
EBITDA growth | 0.2% | -449.3% | -139.6% | 126.4% | -214.6% | -183.1% | 131.2% | 161.0% |
EBITDA margin | 19.4% | 22.0% | -7.1% | 22.1% | 11.2% | -11.9% | 20.0% | 12.7% |
Depreciation | 46.4 | 36.3 | 30.3 | 33.0 | 33.5 | 30.7 | 45.8 | 44.9 |
EBITA | 613.1 | 622.0 | -218.8 | 443.2 | 176.9 | -214.2 | 175.0 | 50.7 |
EBITA margin | 18.1% | 20.8% | -8.2% | 20.5% | 9.4% | -13.9% | 15.8% | 6.7% |
Amortization of intangibles | 21.5 | 21.5 | 21.5 | 21.5 | 21.5 | 21.5 | 12.6 | |
EBIT [+] | 591.6 | 600.5 | -240.3 | 421.7 | 155.4 | -235.7 | 162.4 | 50.7 |
EBIT growth | -1.5% | -349.9% | -157.0% | 171.4% | -165.9% | -245.1% | 220.7% | -1154.4% |
EBIT margin | 17.4% | 20.1% | -9.0% | 19.5% | 8.3% | -15.3% | 14.7% | 6.7% |
Non-recurring items [+] | 12.1 | 14.7 | 23.4 | 19.7 | 26.2 | 7.7 | 17.4 | |
Loss on contingent liability | 12.1 | 14.7 | 23.4 | 19.7 | 26.2 | 7.7 | 17.4 | |
Interest expense, net [+] | 2.7 | 1.9 | 2.2 | 1.9 | 1.5 | 6.9 | 34.3 | 38.5 |
Interest expense | 2.7 | 1.9 | 2.2 | 1.9 | 1.5 | 6.9 | 38.7 | 45.6 |
Interest income | | | | | | | 4.4 | 7.1 |
Other income (expense), net [+] | -47.7 | -13.4 | 33.6 | 86.6 | -12.3 | -62.0 | -3.3 | -4.6 |
Other | 39.9 | 10.6 | 23.2 | 52.2 | 31.8 | 17.2 | | |
Pre-tax income | 529.1 | 570.4 | -232.2 | 486.8 | 115.3 | -312.3 | 107.4 | 7.6 |
Income taxes | 188.5 | -378.1 | 63.5 | 39.9 | 5.9 | 0.9 | 3.2 | 1.0 |
Tax rate | 35.6% | | | 8.2% | 5.1% | | 3.0% | 13.6% |
Net income | 340.7 | 948.6 | -295.7 | 446.9 | 109.5 | -313.1 | 104.2 | 6.5 |
Net margin | 10.0% | 31.8% | -11.1% | 20.7% | 5.8% | -20.4% | 9.4% | 0.9% |
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Basic EPS [+] | $1.53 | $4.30 | ($1.36) | $2.08 | $0.52 | ($1.53) | $0.55 | $0.04 |
Growth | -64.3% | -417.4% | -165.2% | 303.4% | -133.7% | -375.9% | 1425.5% | -112.6% |
Diluted EPS [+] | $1.52 | $4.27 | ($1.36) | $2.05 | $0.51 | ($1.53) | $0.54 | $0.03 |
Growth | -64.4% | -415.0% | -166.0% | 304.4% | -133.2% | -385.1% | 1439.7% | -112.1% |
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Shares outstanding (basic) [+] | 222.0 | 220.4 | 218.1 | 214.9 | 212.4 | 204.6 | 187.9 | 179.6 |
Growth | 0.7% | 1.1% | 1.5% | 1.2% | 3.8% | 8.9% | 4.6% | 6.9% |
Shares outstanding (diluted) [+] | 224.0 | 222.1 | 218.1 | 217.7 | 215.6 | 204.6 | 194.1 | 187.3 |
Growth | 0.8% | 1.8% | 0.2% | 0.9% | 5.4% | 5.4% | 3.6% | 11.5% |
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EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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