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| In millions, except per share items | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 |
| | 10-K | 10-K | 10-K | 10-K | 10-K |
| Revenues: |
| UNITED STATES | 258.3 | 154.8 | 133.3 | | |
| China | 74.9 | 41.7 | 29.9 | 15.1 | 3.2 |
| Other | 157.3 | 102.3 | 82.7 | 131.2 | 67.9 |
| Total revenues | 490.5 | 298.8 | 245.9 | 146.3 | 71.1 |
| Revenue growth [+] | 64.1% | 21.5% | 68.1% | 105.8% | |
| UNITED STATES | 66.9% | 16.1% | | | |
| China | 79.5% | 39.5% | 98.5% | 375.4% | |
| Cost of goods sold | 74.1 | 58.5 | 61.0 | 28.7 | 10.6 |
| Gross profit | 416.4 | 240.4 | 184.9 | 117.7 | 60.5 |
| Gross margin | 84.9% | 80.4% | 75.2% | 80.4% | 85.1% |
| Selling, general and administrative | 257.6 | 202.3 | 130.8 | 87.9 | 46.7 |
| Research and development | 211.8 | 123.4 | 83.1 | 47.5 | 32.2 |
| Other operating expenses | -0.7 | 1.3 | 1.5 | 30.6 | |
| EBITDA [+] | -31.1 | -72.6 | -23.5 | -44.5 | -14.1 |
| EBITDA growth | -57.1% | 208.8% | -47.2% | 216.2% | |
| EBITDA margin | -6.3% | -24.3% | -9.6% | -30.4% | -19.8% |
| Depreciation and amortization | 21.1 | 14.0 | 7.1 | 3.9 | 4.3 |
| EBIT [+] | -52.3 | -86.6 | -30.6 | -48.4 | -18.4 |
| EBIT growth | -39.7% | 183.2% | -36.8% | 163.4% | |
| EBIT margin | -10.7% | -29.0% | -12.4% | -33.1% | -25.8% |
| Non-recurring items [+] | | 447.5 | | 62.4 | |
| In-process research & development | | 447.5 | | 62.4 | |
| Interest expense, net [+] | 0.7 | 0.2 | 0.3 | 1.4 | 0.5 |
| Interest expense | 0.9 | 1.7 | 3.1 | 2.4 | 0.8 |
| Interest income | 0.2 | 1.5 | 2.8 | 1.0 | 0.3 |
| Other income (expense), net [+] | -0.8 | -0.2 | -0.2 | -0.2 | 0.1 |
| Gain (loss) on debt retirement | | -1.5 | | | |
| Other | -0.8 | 1.3 | -0.2 | -0.2 | 0.1 |
| Pre-tax income | -53.7 | -534.5 | -31.0 | -112.4 | -18.7 |
| Income taxes | 4.5 | 8.3 | 0.2 | 0.1 | 0.0 |
| Net income | -58.2 | -542.7 | -31.3 | -112.5 | -18.8 |
| Net margin | -11.9% | -181.6% | -12.7% | -76.9% | -26.4% |
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| Basic EPS [+] | ($0.53) | ($5.37) | ($0.80) | ($8.40) | ($1.62) |
| Growth | -90.2% | 571.2% | -90.5% | 418.8% | |
| Diluted EPS [+] | ($0.53) | ($5.37) | ($0.80) | ($8.40) | ($1.62) |
| Growth | -90.2% | 571.2% | -90.5% | 418.8% | |
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| Shares outstanding (basic) [+] | 110.3 | 101.2 | 39.1 | 13.4 | 11.6 |
| Growth | 9.1% | 158.8% | 191.9% | 15.6% | |
| Shares outstanding (diluted) [+] | 110.3 | 101.2 | 39.1 | 13.4 | 11.6 |
| Growth | 9.1% | 158.8% | 191.9% | 15.6% | |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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