| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/31/2023 | Smith Julie Diana | Sr VP, Controller, PAO | Disposition | Common Stock | 25.6k | $0.00 | $0 | By Spouse | 01/31/2023 |
| 01/31/2023 | Smith Julie Diana | Sr VP, Controller, PAO | Grant | Common Stock | 2.6k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Smith Julie Diana | Sr VP, Controller, PAO | Disposition | Common Stock | 32.7k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Smith Julie Diana | Sr VP, Controller, PAO | Disposition | Stock Option (Right to Buy) | 2k | $6.97 | $13.9k | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Grant | Common Stock | 7.9k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Disposition | Common Stock | 43.3k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Disposition | Stock Option (Right to Buy) | 10k | $14.60 | $146k | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Disposition | Stock Option (Right to Buy) | 4k | $6.97 | $27.9k | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Disposition | Stock Option (Right to Buy) | 12.1k | $18.48 | $223.7k | | 01/31/2023 |
| 01/31/2023 | Serafini-Lamanna Tony | Executive VP-Diagnostics | Disposition | Stock Option (Right to Buy) | 11.7k | $18.88 | $220.3k | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Grant | Common Stock | 7.9k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Disposition | Common Stock | 86k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Disposition | Stock Option (Right to Buy) | 10k | $19.66 | $196.6k | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Disposition | Stock Option (Right to Buy) | 2.5k | $14.30 | $35.8k | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Disposition | Stock Option (Right to Buy) | 12.1k | $18.48 | $223.7k | | 01/31/2023 |
| 01/31/2023 | WELTZIEN LOURDES | Executive VP, Life Science | Disposition | Stock Option (Right to Buy) | 11.7k | $18.88 | $220.3k | | 01/31/2023 |
| 01/31/2023 | Kitzmiller Andrew S. | Executive Vice President & CFO | Grant | Common Stock | 7.9k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Kitzmiller Andrew S. | Executive Vice President & CFO | Disposition | Common Stock | 19.5k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Kitzmiller Andrew S. | Executive Vice President & CFO | Disposition | Stock Option (Right to Buy) | 5k | $24.74 | $123.7k | | 01/31/2023 |
| 01/31/2023 | Kenny John P. | CEO | Grant | Common Stock | 47.1k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Kenny John P. | CEO | Disposition | Common Stock | 267.7k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Kenny John P. | CEO | Disposition | Stock Option (Right to Buy) | 66k | $10.10 | $667k | | 01/31/2023 |
| 01/31/2023 | Kenny John P. | CEO | Disposition | Stock Option (Right to Buy) | 83.5k | $18.48 | $1.5M | | 01/31/2023 |
| 01/31/2023 | Kenny John P. | CEO | Disposition | Stock Option (Right to Buy) | 82.9k | $18.88 | $1.6M | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Common Stock | 28.2k | $0.00 | $0 | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Common Stock | 5k | $0.00 | $0 | By Spouse | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 8.5k | $25.83 | $219.6k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 8.5k | $17.34 | $147.4k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 8.5k | $18.64 | $158.4k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 12k | $12.80 | $153.6k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 12k | $16.20 | $194.4k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 8.7k | $16.97 | $148.3k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 17.2k | $10.46 | $180k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 5.8k | $21.36 | $123.8k | | 01/31/2023 |
| 01/31/2023 | Anderson James M. | Director | Disposition | Stock Option (Right to Buy) | 5.7k | $20.75 | $117.4k | | 01/31/2023 |
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