Type	Name	Date
Securities purchase agreement	Securities Purchase Agreement, by and among the Company and the Purchasers	04/13/2023
Securities purchase agreement	Securities Purchase Agreement, by and among the Company and the Purchasers	11/30/2021
Securities purchase agreement	Securities Purchase Agreement, by and among the Company and the Purchasers	12/04/2020
Securities purchase agreement	Securities Purchase Agreement, by and among the Company and the Purchasers	05/09/2019
Underwriting agreement	Underwriting Agreement	10/29/2014

Type	Name	Date
By-Laws	Amended and Restated Bylaws of Regulus Therapeutics Inc	12/05/2014
By-Laws	Amended and Restated Bylaws of Regulus Therapeutics Inc	10/11/2012

Type	Name	Date
Equity incentive plans	Regulus Therapeutics Inc. 2019 Equity Incentive Plan	08/06/2019
Equity incentive plans	Regulus Therapeutics Inc. 2019 Equity Incentive Plan	08/06/2019
Employment agreement	Amended and Restated Employment Agreement, by and between Regulus Therapeutics Inc. and Daniel R. Chevallard	05/26/2017
Employment agreement	Amended and Restated Employment Agreement, by and between Regulus Therapeutics Inc. and Daniel R. Chevallard	05/26/2017
Employment agreement	Amended and Restated Employment Agreement by and between Regulus Therapeutics Inc. and Neil W. Gibson, Ph.D.	09/19/2014
Employment agreement	Amended and Restated Employment Agreement by and between Regulus Therapeutics Inc. and Paul C. Grint, M.D.	09/19/2014
Employment agreement	Amended and Restated Employment Agreement by and between Regulus Therapeutics Inc. and David L. Szekeres	09/19/2014

Type	Name	Date
Lease agreement	Fifth Amendment to Lease, by and between BMR-3545-3575 JOHN HOPKINS LP and Regulus Therapeutics Inc	06/26/2013