Financial Summary (All financials)
| In millions, except per share items | Dec-31-22 | Dec-31-21 | Dec-31-20 | Dec-31-19 | Dec-31-18 | Dec-31-17 | Dec-31-16 | Dec-31-15 |
| Revenues | 3,394.6 | 2,986.3 | 2,666.7 | 2,158.8 | 1,881.9 | 1,536.2 | 1,105.7 | 753.8 |
| Revenue growth | 13.7% | 12.0% | 23.5% | 14.7% | 22.5% | 38.9% | 46.7% | 47.4% |
| Cost of goods sold | 207.0 | 151.0 | 131.3 | 114.2 | 94.1 | 79.5 | 58.2 | 27.0 |
| Gross profit | 3,187.6 | 2,835.3 | 2,535.4 | 2,044.5 | 1,787.8 | 1,456.7 | 1,047.5 | 726.8 |
| Gross margin | 93.9% | 94.9% | 95.1% | 94.7% | 95.0% | 94.8% | 94.7% | 96.4% |
| Selling, general and administrative | 1,002.1 | 739.6 | 516.9 | 468.7 | 434.4 | 366.3 | 303.3 | 196.6 |
| Research and development | 1,585.9 | 1,458.2 | 2,215.9 | 1,154.1 | 1,198.0 | 1,326.1 | 581.9 | 479.5 |
| EBITA | 613.1 | 622.0 | -218.8 | 443.2 | 176.9 | -214.2 | 175.0 | 50.7 |
| EBITA margin | 18.1% | 20.8% | -8.2% | 20.5% | 9.4% | -13.9% | 15.8% | 6.7% |
| Amortization of intangibles | 21.5 | 21.5 | 21.5 | 21.5 | 21.5 | 21.5 | 12.6 | |
| EBIT | 591.6 | 600.5 | -240.3 | 421.7 | 155.4 | -235.7 | 162.4 | 50.7 |
| EBIT margin | 17.4% | 20.1% | -9.0% | 19.5% | 8.3% | -15.3% | 14.7% | 6.7% |
| Pre-tax income | 529.1 | 570.4 | -232.2 | 486.8 | 115.3 | -312.3 | 107.4 | 7.6 |
| Income taxes | 188.5 | -378.1 | 63.5 | 39.9 | 5.9 | 0.9 | 3.2 | 1.0 |
| Tax rate | 35.6% | | | 8.2% | 5.1% | | 3.0% | 13.6% |
| Net income | 340.7 | 948.6 | -295.7 | 446.9 | 109.5 | -313.1 | 104.2 | 6.5 |
| Net margin | 10.0% | 31.8% | -11.1% | 20.7% | 5.8% | -20.4% | 9.4% | 0.9% |
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| Diluted EPS | $1.52 | $4.27 | ($1.36) | $2.05 | $0.51 | ($1.53) | $0.54 | $0.03 |
| Shares outstanding (diluted) | 224.0 | 222.1 | 218.1 | 217.7 | 215.6 | 204.6 | 194.1 | 187.3 |
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| EBIT is a non-GAAP figure that excludes all non-recurring expenses: restructuring costs, asset impairments, IPR&D writeoffs, and other unusual charges. |
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