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FRED ALGER MANAGEMENT, LLC
> REGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | REGENERON PHARMACEUTICALS, INC. | REGN | 84 | -12,475 | 60,357,000 | 51,705,000 | $718,535.71 |
| 09/30/2022 | REGENERON PHARMACEUTICALS, INC. | REGN | 12,559 | 12,559 | 8,652,000 | 8,652,000 | $688.91 |
| 12/31/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -10,557 | 0 | -5,910,000 | |
| 09/30/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 10,557 | -1,500 | 5,910,000 | -1,609,000 | $559.82 |
| 06/30/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 12,057 | 1,242 | 7,519,000 | 2,238,000 | $623.62 |
| 03/31/2020 | REGENERON PHARMACEUTICALS, INC. | REGN | 10,815 | 10,815 | 5,281,000 | 5,281,000 | $488.30 |
| 09/30/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -31 | 0 | -10,000 | |
| 06/30/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 31 | -80,712 | 10,000 | -33,145,000 | $322.58 |
| 03/31/2019 | REGENERON PHARMACEUTICALS, INC. | REGN | 80,743 | 80,743 | 33,155,000 | 33,155,000 | $410.62 |
| 09/30/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -1,000 | 0 | -345,000 | |
| 06/30/2018 | REGENERON PHARMACEUTICALS, INC. | REGN | 1,000 | 1,000 | 345,000 | 345,000 | $345.00 |
| 12/31/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -4,000 | 0 | -1,788,000 | |
| 09/30/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 4,000 | -2,000 | 1,788,000 | -1,159,000 | $447.00 |
| 06/30/2017 | REGENERON PHARMACEUTICALS, INC. | REGN | 6,000 | 6,000 | 2,947,000 | 2,947,000 | $491.17 |
| 03/31/2016 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -62,962 | 0 | -34,180,000 | |
| 12/31/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 62,962 | 14,373 | 34,180,000 | 23,253,000 | $542.87 |
| 09/30/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 65,079 | 16,490 | 30,271,000 | 19,344,000 | $465.14 |
| 06/30/2015 | REGENERON PHARMACEUTICALS, INC. | REGN | 10,100 | -38,489 | 5,152,000 | -5,775,000 | $510.10 |
| 12/31/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -59,108 | 0 | -18,493,000 | |
| 09/30/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 59,108 | 10,519 | 18,493,000 | 7,566,000 | $312.87 |
| 06/30/2013 | REGENERON PHARMACEUTICALS, INC. | REGN | 48,589 | 48,589 | 10,927,000 | 10,927,000 | $224.89 |
| 06/30/2012 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -96,492 | 0 | -11,253,000 | |
| 03/31/2012 | REGENERON PHARMACEUTICALS, INC. | REGN | 96,492 | 96,492 | 11,253,000 | 11,253,000 | $116.62 |
| 09/30/2008 | REGENERON PHARMACEUTICALS, INC. | REGN | 0 | -1,244,019 | 0 | -22,144,000 | |
| 09/30/2007 | REGENERON PHARMACEUTICALS, INC. | REGN | 1,244,019 | -723,992 | 22,144,000 | -13,123,000 | $17.80 |
| 06/30/2007 | REGENERON PHARMACEUTICALS, INC. | REGN | 1,968,011 | 1,451,079 | 35,267,000 | 24,892,000 | $17.92 |
| 12/31/2006 | REGENERON PHARMACEUTICALS, INC. | REGN | 516,932 | -215,878 | 10,375,000 | -1,123,000 | $20.07 |
| 09/30/2006 | REGENERON PHARMACEUTICALS, INC. | REGN | 732,810 | 522,630 | 11,498,000 | 6,246,000 | $15.69 |
| 03/31/2002 | REGENERON PHARMACEUTICALS, INC. | REGN | 210,180 | -14,150 | 5,252,000 | -1,065,000 | $24.99 |
| 12/31/2001 | REGENERON PHARMACEUTICALS, INC. | REGN | 224,330 | 224,330 | 6,317,000 | 6,317,000 | $28.16 |
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