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FMR LLC
> PRTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 7,912,766 | 1,150,741 | 540,283,662,000 | 212,528,311,000 | $68,280.00 |
| 03/31/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 6,762,025 | 3,599,607 | 327,755,351,000 | 327,563,613,000 | $48,470.00 |
| 09/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 3,162,418 | 237,020 | 191,738,000 | 112,313,000 | $60.63 |
| 06/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 2,925,398 | 249,784 | 79,425,000 | -18,423,000 | $27.15 |
| 03/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 2,675,614 | 33,873 | 97,848,000 | -32,655,000 | $36.57 |
| 12/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 2,641,741 | -7,690 | 130,503,000 | -58,216,000 | $49.40 |
| 09/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 2,649,431 | -128,856 | 188,719,000 | 45,887,000 | $71.23 |
| 06/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 2,778,287 | -337,909 | 142,832,000 | 64,553,000 | $51.41 |
| 03/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 3,116,196 | 1,633,835 | 78,279,000 | 60,476,000 | $25.12 |
| 02/08/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,482,361 | 0 | 23,006,243 | 5,203,243 | $15.52 |
| 12/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,482,361 | -516,509 | 17,803,000 | -2,166,000 | $12.01 |
| 09/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,998,870 | 41,121 | 19,969,000 | -509,000 | $9.99 |
| 06/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,957,749 | -1,175,504 | 20,478,000 | -13,048,000 | $10.46 |
| 03/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 3,133,253 | -194,096 | 33,526,000 | -19,146,000 | $10.70 |
| 12/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 3,327,349 | -45,210 | 52,672,000 | 26,231,000 | $15.83 |
| 09/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 3,372,559 | -722,610 | 26,441,000 | -16,845,000 | $7.84 |
| 06/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,095,169 | -91,864 | 43,286,000 | -7,503,000 | $10.57 |
| 03/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,187,033 | -723,397 | 50,789,000 | 212,000 | $12.13 |
| 02/13/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,910,430 | -131,934 | 62,607,983 | -3,346,018 | $12.75 |
| 12/31/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,910,430 | -131,934 | 50,577,000 | -15,377,000 | $10.30 |
| 09/30/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,042,364 | -525,958 | 65,954,000 | -15,232,000 | $13.08 |
| 06/30/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,568,322 | -207,958 | 81,186,000 | -130,861,000 | $14.58 |
| 03/31/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,776,280 | 14,066 | 212,047,000 | -3,978,000 | $36.71 |
| 12/31/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,762,214 | 20,952 | 216,025,000 | -155,837,000 | $37.49 |
| 09/30/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,741,262 | 42,028 | 371,862,000 | 371,553,557 | $64.77 |
| 06/30/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,699,234 | 39,926 | 308,443 | -315,424,557 | $0.05 |
| 03/31/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,659,308 | 486,044 | 315,733,000 | 61,260,000 | $55.79 |
| 12/31/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,173,264 | 13,883 | 254,473,000 | -54,935,000 | $49.19 |
| 09/30/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,159,381 | 5,159,381 | 309,408,000 | 309,408,000 | $59.97 |
| 06/30/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,147,581 | 1,572 | 179,959,000 | -31,851,000 | $34.96 |
| 03/31/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 5,146,009 | 417,597 | 211,810,000 | -110,242,000 | $41.16 |
| 12/31/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,728,412 | 25,615 | 322,052,000 | 108,827,000 | $68.11 |
| 09/30/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,702,797 | 9,915 | 213,225,000 | -33,949,000 | $45.34 |
| 06/30/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,692,882 | 582,952 | 247,174,000 | 90,421,000 | $52.67 |
| 03/31/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 4,109,930 | 2,312 | 156,753,000 | 71,479,000 | $38.14 |
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