KHANNA ASHISH [Rocket]

Date	Name	Symbol	Type	Security	Shares	Price	Value	Ownership	Reported
01/03/2023	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	375k	$0.36	$135k		01/03/2023
02/17/2022	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	375k	$3.60	$1.4M		02/17/2022
12/02/2021	Aptinyx Inc.	APTX	Purchase	Common Stock	45k	$2.26	$101.7k		12/02/2021
05/17/2021	Aptinyx Inc.	APTX	Exercise	Restricted Stock Units	130k	$0.00	$0		05/17/2021
05/17/2021	Aptinyx Inc.	APTX	Payment of Exercise	Common Stock	38.1k	$2.53	$96.4k		05/17/2021
05/17/2021	Aptinyx Inc.	APTX	Exercise	Restricted Stock Units	130k	$0.00	$0		05/17/2021
05/17/2021	Aptinyx Inc.	APTX	Payment of Exercise	Common Stock	38.1k	$2.53	$96.4k		05/17/2021
02/24/2021	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	303.4k	$3.80	$1.2M		02/24/2021
02/26/2020	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	230k	$3.12	$717.6k		02/26/2020
05/16/2019	Aptinyx Inc.	APTX	Grant	Restricted Stock Units	130k	$0.00	$0		05/16/2019
01/18/2019	Aptinyx Inc.	APTX	Purchase	Common Stock	10k	$5.45	$54.5k		01/18/2019
01/04/2019	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	90k	$19.33	$1.7M		01/04/2019
09/20/2018	Aptinyx Inc.	APTX	Grant	Stock Option (Right to Buy)	30k	$27.43	$822.9k		09/20/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Common Stock	5.3k	$0.00	$0		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Common Stock	6k	$0.00	$0		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Common Stock	4.1k	$0.00	$0		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Purchase	Common Stock	6k	$16.00	$96k		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Purchase	Common Stock	1.8k	$16.00	$28.8k	By family member	06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Series A-1 Convertible Preferred Stock	145.9k	$0.00	$0		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Series A-2 Convertible Preferred Stock	166.8k	$0.00	$0		06/25/2018
06/25/2018	Aptinyx Inc.	APTX	Conversion	Series B Convertible Preferred Stock	113k	$0.00	$0		06/25/2018