News + Filings Holdings
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MANUFACTURERS LIFE INSURANCE COMPANY, THE
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 928,417 | 16,131 | 326,719,226,000 | 39,285,276,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 912,286 | 162,491 | 287,433,950,000 | 287,222,907,000 | $315,070.00 |
| 12/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 838,863 | 86,980 | 242,296,279,000 | 24,039,453,000 | $288,838.92 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 751,883 | 2,088 | 218,256,826,000 | 218,045,783,000 | $290,280.30 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 749,795 | 111,201 | 211,043,216,000 | 45,109,576,000 | $281,467.89 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 638,594 | 161,674 | 165,933,640,000 | 165,828,299,000 | $259,842.15 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 476,920 | -116,047 | 105,341,000 | -2,217,000 | $220.88 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 592,967 | -5,773 | 107,558,000 | -13,165,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 598,740 | 170,032 | 120,723,000 | 19,403,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 428,708 | 183,432 | 101,320,000 | 34,576,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 245,276 | -31,450 | 66,744,000 | -12,172,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 276,726 | -2,928 | 78,916,000 | 12,372,000 | $285.18 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 279,654 | 38,355 | 66,544,000 | 13,711,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 241,299 | -7,069 | 52,833,000 | 11,421,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 248,368 | 9,405 | 41,412,000 | -2,409,000 | $166.74 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 238,963 | -22,329 | 43,821,000 | -4,243,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 261,292 | -41,987 | 48,064,000 | -2,193,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 303,279 | -13,370 | 50,257,000 | -10,774,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 316,649 | 44,742 | 61,031,000 | 14,818,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 271,907 | 23,694 | 46,213,000 | 5,760,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 248,213 | -65,168 | 40,453,000 | -6,511,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 313,381 | 33,614 | 46,964,000 | 4,428,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 279,767 | 5,530 | 42,536,000 | 7,195,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 274,237 | 165,957 | 35,341,000 | 23,501,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 108,280 | -150,110 | 11,840,000 | -7,195,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 258,390 | 258,117 | 19,035,000 | 19,011,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 273 | -421,599 | 24,000 | -36,265,000 | $87.91 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 421,872 | -100,665 | 36,289,000 | -4,678,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 522,537 | 519,752 | 40,967,000 | 40,850,000 | $78.40 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 246,101 | -8,997 | 30,967,000 | 4,401,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 255,098 | 252,313 | 26,566,000 | 26,449,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 246,020 | -1,847 | 30,379,000 | 1,138,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 247,867 | 13,938 | 29,241,000 | 12,697,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 253,063 | 19,134 | 30,064,000 | 13,520,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 240,800 | 6,871 | 27,045,000 | 10,501,000 | $112.31 |
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