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VANGUARD GROUP INC
> KPTI
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Karyopharm Therapeutics Inc. | KPTI | 8,684,128 | 3,870,729 | 15,544,589,000 | 15,518,307,000 | $1,790.00 |
| 09/30/2022 | Karyopharm Therapeutics Inc. | KPTI | 4,813,399 | 591,419 | 26,282,000 | 7,241,000 | $5.46 |
| 06/30/2022 | Karyopharm Therapeutics Inc. | KPTI | 4,221,980 | 261,272 | 19,041,000 | -10,149,000 | $4.51 |
| 03/31/2022 | Karyopharm Therapeutics Inc. | KPTI | 3,960,708 | 601,901 | 29,190,000 | 7,593,000 | $7.37 |
| 12/31/2021 | Karyopharm Therapeutics Inc. | KPTI | 3,358,807 | -283,892 | 21,597,000 | 396,000 | $6.43 |
| 09/30/2021 | Karyopharm Therapeutics Inc. | KPTI | 3,642,699 | 29,363 | 21,201,000 | -16,089,000 | $5.82 |
| 06/30/2021 | Karyopharm Therapeutics Inc. | KPTI | 3,613,336 | 132,937 | 37,290,000 | -16,587,000 | $10.32 |
| 12/31/2020 | Karyopharm Therapeutics Inc. | KPTI | 3,480,399 | 36,334 | 53,877,000 | 3,593,000 | $15.48 |
| 09/30/2020 | Karyopharm Therapeutics Inc. | KPTI | 3,444,065 | -119,940 | 50,284,000 | -17,217,000 | $14.60 |
| 06/30/2020 | Karyopharm Therapeutics Inc. | KPTI | 3,564,005 | 315,546 | 67,501,000 | 5,098,000 | $18.94 |
| 03/31/2020 | Karyopharm Therapeutics Inc. | KPTI | 3,248,459 | 482,568 | 62,403,000 | 9,380,000 | $19.21 |
| 12/31/2019 | Karyopharm Therapeutics Inc. | KPTI | 2,765,891 | 21,330 | 53,023,000 | 26,621,000 | $19.17 |
| 09/30/2019 | Karyopharm Therapeutics Inc. | KPTI | 2,744,561 | -239,301 | 26,402,000 | 8,528,000 | $9.62 |
| 06/30/2019 | Karyopharm Therapeutics Inc. | KPTI | 2,983,862 | 369,590 | 17,874,000 | 2,607,000 | $5.99 |
| 03/31/2019 | Karyopharm Therapeutics Inc. | KPTI | 2,614,272 | 885,385 | 15,267,000 | -932,000 | $5.84 |
| 12/31/2018 | Karyopharm Therapeutics Inc. | KPTI | 1,728,887 | -683,995 | 16,199,000 | -24,893,000 | $9.37 |
| 09/30/2018 | Karyopharm Therapeutics Inc. | KPTI | 2,412,882 | -80,332 | 41,092,000 | -1,268,000 | $17.03 |
| 06/30/2018 | Karyopharm Therapeutics Inc. | KPTI | 2,493,214 | 557,171 | 42,360,000 | 16,379,000 | $16.99 |
| 03/31/2018 | Karyopharm Therapeutics Inc. | KPTI | 1,936,043 | 134,652 | 25,981,000 | 8,688,000 | $13.42 |
| 12/31/2017 | Karyopharm Therapeutics Inc. | KPTI | 1,801,391 | 31,725 | 17,293,000 | -2,138,000 | $9.60 |
| 09/30/2017 | Karyopharm Therapeutics Inc. | KPTI | 1,769,666 | 148,246 | 19,431,000 | 19,416,325 | $10.98 |
| 06/30/2017 | Karyopharm Therapeutics Inc. | KPTI | 1,621,420 | 384,658 | 14,675 | -15,865,325 | $0.01 |
| 03/31/2017 | Karyopharm Therapeutics Inc. | KPTI | 1,236,762 | 110,093 | 15,880,000 | 5,289,000 | $12.84 |
| 12/31/2016 | Karyopharm Therapeutics Inc. | KPTI | 1,126,669 | 245,064 | 10,591,000 | 2,013,000 | $9.40 |
| 09/30/2016 | Karyopharm Therapeutics Inc. | KPTI | 881,605 | 881,605 | 8,578,000 | 8,578,000 | $9.73 |
| 06/30/2016 | Karyopharm Therapeutics Inc. | KPTI | 816,444 | 127,714 | 5,478,000 | -666,000 | $6.71 |
| 03/31/2016 | Karyopharm Therapeutics Inc. | KPTI | 688,730 | -9,531 | 6,144,000 | -1,209,000 | $8.92 |
| 12/31/2015 | Karyopharm Therapeutics Inc. | KPTI | 702,058 | 3,797 | 9,302,000 | 1,949,000 | $13.25 |
| 09/30/2015 | Karyopharm Therapeutics Inc. | KPTI | 698,261 | -2,455 | 7,353,000 | -11,714,000 | $10.53 |
| 06/30/2015 | Karyopharm Therapeutics Inc. | KPTI | 700,716 | 138,667 | 19,067,000 | 1,863,000 | $27.21 |
| 03/31/2015 | Karyopharm Therapeutics Inc. | KPTI | 562,049 | 146,360 | 17,204,000 | 1,645,000 | $30.61 |
| 12/31/2014 | Karyopharm Therapeutics Inc. | KPTI | 415,689 | 34,492 | 15,559,000 | 2,240,000 | $37.43 |
| 09/30/2014 | Karyopharm Therapeutics Inc. | KPTI | 381,197 | 381,197 | 13,319,000 | 13,319,000 | $34.94 |
| 06/30/2014 | Karyopharm Therapeutics Inc. | KPTI | 296,407 | 296,407 | 13,798,000 | 13,798,000 | $46.55 |
| 03/31/2014 | Karyopharm Therapeutics Inc. | KPTI | 143,596 | 143,596 | 4,435,000 | 4,435,000 | $30.89 |
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