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NORTHERN TRUST CORP
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,682,024 | -94,671 | 943,831,066,000 | 68,977,773,000 | $351,910.00 |
| 03/31/2023 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,776,695 | -111,303 | 874,853,293,000 | 874,017,102,000 | $315,070.00 |
| 09/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,887,998 | -48,936 | 836,191,000 | 8,593,000 | $289.54 |
| 06/30/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,936,934 | 46,981 | 827,598,000 | 73,407,000 | $281.79 |
| 03/31/2022 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,889,953 | -18,399 | 754,191,000 | 115,517,000 | $260.97 |
| 12/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,908,352 | -86,138 | 638,674,000 | 95,503,000 | $219.60 |
| 09/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,994,490 | 21,674 | 543,171,000 | -56,237,000 | $181.39 |
| 06/30/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,972,816 | -49,688 | 599,408,000 | -114,929,000 | $201.63 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,022,504 | -75,401 | 714,337,000 | -128,665,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,097,905 | 237,946 | 843,002,000 | 162,474,000 | $272.12 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,859,959 | 18,222 | 680,528,000 | 58,329,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,841,737 | -110,483 | 622,199,000 | 122,035,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,952,220 | 8,440 | 500,164,000 | -39,666,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,943,780 | 33,009 | 539,830,000 | 4,393,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,910,771 | 31,978 | 535,437,000 | 58,393,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,878,793 | 98,585 | 477,044,000 | -58,813,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,780,208 | -22,732 | 535,857,000 | 59,469,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,802,940 | -6,684 | 476,388,000 | 18,475,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,809,624 | -33,696 | 457,913,000 | 31,813,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,843,320 | -50,060 | 426,100,000 | -13,810,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,893,380 | 182,130 | 439,910,000 | 90,510,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,711,250 | 6,055 | 349,400,000 | 53,587,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,705,195 | 2,705,195 | 295,813,000 | 295,813,000 | $109.35 |
| 09/30/2009 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -73,457 | 0 | -2,282,000 | |
| 03/31/2009 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -73,457 | 0 | -2,282,000 | |
| 09/30/1999 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 73,457 | 7,300 | 2,282,000 | 686,000 | $31.07 |
| 06/30/1999 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 66,157 | -2,800 | 1,596,000 | -145,000 | $24.12 |
| 03/31/1999 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 68,957 | 68,957 | 1,741,000 | 1,741,000 | $25.25 |
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