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GREAT LAKES ADVISORS, LLC
> TMO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 198,366 | -41,947 | 103,498,351,000 | -35,011,070,000 | $521,754.49 |
| 03/31/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 240,313 | 232,828 | 138,509,421,000 | 134,387,473,000 | $576,370.90 |
| 12/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,485 | -312 | 4,121,948,000 | 4,117,993,000 | $550,694.46 |
| 09/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,797 | -1,150 | 3,955,000 | -906,000 | $507.25 |
| 06/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 8,947 | 785 | 4,861,000 | 40,000 | $543.31 |
| 03/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 8,162 | -369 | 4,821,000 | -871,000 | $590.66 |
| 12/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 8,531 | -239 | 5,692,000 | 681,000 | $667.21 |
| 09/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 8,770 | -325 | 5,011,000 | 423,000 | $571.38 |
| 06/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,095 | 1,693 | 4,588,000 | 1,210,000 | $504.45 |
| 03/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,402 | -152 | 3,378,000 | -141,000 | $456.36 |
| 12/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,554 | -3,152 | 3,519,000 | -1,208,000 | $465.85 |
| 09/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 10,706 | 667 | 4,727,000 | 1,089,000 | $441.53 |
| 06/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 10,039 | -2,299 | 3,638,000 | 139,000 | $362.39 |
| 03/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 12,338 | 5,459 | 3,499,000 | 1,264,000 | $283.60 |
| 12/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,879 | 48 | 2,235,000 | 245,000 | $324.90 |
| 09/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,831 | 141 | 1,990,000 | 25,000 | $291.32 |
| 06/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,690 | -156 | 1,965,000 | 91,000 | $293.72 |
| 03/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,846 | -9,043 | 1,874,000 | -1,682,000 | $273.74 |
| 12/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 15,889 | -440 | 3,556,000 | -430,000 | $223.80 |
| 09/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 16,329 | 9,447 | 3,986,000 | 2,560,000 | $244.11 |
| 06/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,882 | -57 | 1,426,000 | -7,000 | $207.21 |
| 03/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 6,939 | -2,415 | 1,433,000 | -343,000 | $206.51 |
| 12/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,354 | -362 | 1,776,000 | -62,000 | $189.87 |
| 09/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,716 | -1,742 | 1,838,000 | -161,000 | $189.17 |
| 06/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 11,458 | 2,304 | 1,999,000 | 593,000 | $174.46 |
| 03/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,154 | -3,989 | 1,406,000 | -448,000 | $153.59 |
| 12/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 13,143 | -1,370 | 1,854,000 | -454,000 | $141.06 |
| 09/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 14,513 | -180 | 2,308,000 | 137,000 | $159.03 |
| 06/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 14,693 | -607 | 2,171,000 | 5,000 | $147.76 |
| 03/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 15,300 | 1,155 | 2,166,000 | 1,264,000 | $141.57 |
| 12/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,572 | 3,016 | 1,074,000 | 567,000 | $141.84 |
| 09/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,828 | 3,272 | 957,000 | 450,000 | $122.25 |
| 06/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 7,580 | 3,304 | 984,000 | 479,000 | $129.82 |
| 03/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,132 | 4,856 | 1,227,000 | 722,000 | $134.36 |
| 12/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 9,131 | -75 | 1,144,000 | 24,000 | $125.29 |
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