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BAKER BROS. ADVISORS LP
> BMEA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Biomea Fusion, Inc. | BMEA | 2,108,949 | 4,390 | 46,291,431,000 | 28,549,999,000 | $21,950.00 |
| 12/31/2022 | Biomea Fusion, Inc. | BMEA | 2,104,559 | 0 | 17,741,432,000 | 17,720,849,000 | $8,430.00 |
| 09/30/2022 | Biomea Fusion, Inc. | BMEA | 2,104,559 | 0 | 20,583,000 | -4,630,000 | $9.78 |
| 06/30/2022 | Biomea Fusion, Inc. | BMEA | 2,104,559 | 553,114 | 25,213,000 | 18,294,000 | $11.98 |
| 03/31/2022 | Biomea Fusion, Inc. | BMEA | 1,551,445 | 1,026,828 | 6,919,000 | 3,011,000 | $4.46 |
| 12/31/2021 | Biomea Fusion, Inc. | BMEA | 524,617 | 0 | 3,908,000 | -2,372,000 | $7.45 |
| 09/30/2021 | Biomea Fusion, Inc. | BMEA | 524,617 | 230,500 | 6,280,000 | 1,689,000 | $11.97 |
| 06/30/2021 | Biomea Fusion, Inc. | BMEA | 294,117 | 294,117 | 4,591,000 | 4,591,000 | $15.61 |
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