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MADRIGAL PHARMACEUTICALS, INC. (MDGL)

Portfolio as of:
NameSharesChangeValue% Port% OSHistDate
BAKER BROS. ADVISORS LP 1,545,1130356,921,103,0002.078.45 Hist 06/30/2023
Avoro Capital Advisors LLC 1,515,151-151,515349,999,881,0004.758.28 Hist 06/30/2023
JANUS HENDERSON GROUP PLC 1,484,1261,301,478342,842,709,0000.218.11 Hist 06/30/2023
VANGUARD GROUP INC 1,465,522211,217338,535,582,0000.018.01 Hist 06/30/2023
BlackRock Inc. 1,043,53791,027241,057,047,0000.015.71 Hist 06/30/2023
STATE STREET CORP 543,759-717,234125,608,329,0000.012.97 Hist 06/30/2023
MARSHALL WACE, LLP 460,644460,644106,408,764,0000.212.52 Hist 06/30/2023
ALLIANCEBERNSTEIN L.P. 371,116347,44885,727,796,0000.032.03 Hist 06/30/2023
PAULSON & CO. INC. 350,200350,20080,896,200,0007.901.91 Hist 06/30/2023
FMR LLC 349,04386,60080,628,863,0000.011.91 Hist 06/30/2023
ORBIMED ADVISORS LLC 321,569321,56974,282,439,0001.351.76 Hist 06/30/2023
PERCEPTIVE ADVISORS LLC 302,987-428,94569,989,997,000   Hist 06/30/2023
GEODE CAPITAL MANAGEMENT, LLC 271,31923,26262,674,689,0000.011.48 Hist 06/30/2023
Artisan Partners Limited Partnership 230,09014,32053,150,790,0000.091.26 Hist 06/30/2023
RTW INVESTMENTS, LP 221,562221,56251,180,822,0000.971.21 Hist 06/30/2023
Rock Springs Capital Management LP 199,218-148,90346,019,358,0001.091.09 Hist 06/30/2023
PICTET ASSET MANAGEMENT SA 171,330-7,48539,577,230,0000.050.94 Hist 06/30/2023
GOLDMAN SACHS GROUP INC 142,991-37,41134,640,999,0000.010.79 Hist 03/31/2023
TCG Crossover Management, LLC 149,917034,630,827,0005.680.82 Hist 06/30/2023
ARMISTICE CAPITAL, LLC 136,000-140,00031,416,000,0000.450.74 Hist 06/30/2023
NORTHERN TRUST CORP 122,5999,11428,320,369,0000.010.67 Hist 06/30/2023
Affinity Asset Advisors, LLC 92,500-7,50021,367,500,000   Hist 06/30/2023
JPMORGAN CHASE & CO 88,29134,84920,395,221,0000.000.48 Hist 06/30/2023
EMERALD ADVISERS, LLC 82,06482,06419,880,825,0000.950.45 Hist 03/31/2023
Paradigm Biocapital Advisors LP 85,00085,00019,635,000,0001.520.46 Hist 06/30/2023
CITADEL ADVISORS LLC 83,909-86,37819,382,979,0000.000.46 Hist 06/30/2023
MORGAN STANLEY 74,293-35,12717,161,683,0000.000.41 Hist 06/30/2023
Connor, Clark & Lunn Investment Management Ltd. 65,7615,35415,190,791,0000.080.36 Hist 06/30/2023
Bank of New York Mellon Corp 56,49812,73613,051,038,0000.000.31 Hist 06/30/2023
Ghost Tree Capital, LLC 55,00025,00012,705,000,0004.190.30 Hist 06/30/2023
UniSuper Management Pty Ltd 54,08554,08512,493,635,0000.100.30 Hist 06/30/2023
Caption Management, LLC 52,7001,00012,173,700,0000.220.29 Hist 06/30/2023
EMERALD MUTUAL FUND ADVISERS TRUST 50,073-16,12511,566,863,0000.630.27 Hist 06/30/2023
ADAGE CAPITAL PARTNERS GP, L.L.C. 50,000-56,00011,550,000,0000.030.27 Hist 06/30/2023
AMERICAN CENTURY COMPANIES INC 48,94019,03411,305,211,0000.010.27 Hist 06/30/2023
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