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SPHERA FUNDS MANAGEMENT LTD.
> BIIB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BIOGEN INC. | BIIB | 23,846 | 16,330 | 6,792,533,000 | 4,711,202,000 | $284,850.00 |
| 12/31/2022 | BIOGEN INC. | BIIB | 7,516 | -47,984 | 2,081,331,000 | 2,066,512,000 | $276,920.04 |
| 09/30/2022 | BIOGEN INC. | BIIB | 55,500 | 55,500 | 14,819,000 | 14,819,000 | $267.01 |
| 03/31/2022 | BIOGEN INC. | BIIB | 0 | -13,000 | 0 | -3,119,000 | |
| 12/31/2021 | BIOGEN INC. | BIIB | 13,000 | 13,000 | 3,119,000 | 3,119,000 | $239.92 |
| 09/30/2021 | BIOGEN INC. | BIIB | 0 | -23,995 | 0 | -8,309,000 | |
| 06/30/2021 | BIOGEN INC. | BIIB | 23,995 | 23,995 | 8,309,000 | 8,309,000 | $346.28 |
| 06/30/2019 | BIOGEN INC. | BIIB | 0 | -30,000 | 0 | -7,091,000 | |
| 03/31/2019 | BIOGEN INC. | BIIB | 30,000 | 30,000 | 7,091,000 | 7,091,000 | $236.37 |
| 09/30/2018 | BIOGEN INC. | BIIB | 0 | -50,000 | 0 | -14,512,000 | |
| 06/30/2018 | BIOGEN INC. | BIIB | 50,000 | -15,000 | 14,512,000 | -3,286,000 | $290.24 |
| 03/31/2018 | BIOGEN INC. | BIIB | 65,000 | -9,200 | 17,798,000 | -5,840,000 | $273.82 |
| 12/31/2017 | BIOGEN INC. | BIIB | 74,200 | -30,800 | 23,638,000 | -9,240,000 | $318.57 |
| 09/30/2017 | BIOGEN INC. | BIIB | 105,000 | 15,000 | 32,878,000 | 8,456,000 | $313.12 |
| 06/30/2017 | BIOGEN INC. | BIIB | 90,000 | 15,000 | 24,422,000 | 3,915,000 | $271.36 |
| 03/31/2017 | BIOGEN INC. | BIIB | 75,000 | 75,000 | 20,507,000 | 20,507,000 | $273.43 |
| 12/31/2016 | BIOGEN INC. | BIIB | 0 | -50,000 | 0 | -15,652,000 | |
| 09/30/2016 | BIOGEN INC. | BIIB | 50,000 | -500 | 15,652,000 | 3,440,000 | $313.04 |
| 06/30/2016 | BIOGEN INC. | BIIB | 50,500 | -68,350 | 12,212,000 | -18,727,000 | $241.82 |
| 03/31/2016 | BIOGEN INC. | BIIB | 118,850 | 33,850 | 30,939,000 | 6,135,000 | $260.32 |
| 12/31/2015 | BIOGEN INC. | BIIB | 123,850 | 38,850 | 37,941,000 | 13,137,000 | $306.35 |
| 09/30/2015 | BIOGEN INC. | BIIB | 85,000 | 24,270 | 24,804,000 | 273,000 | $291.81 |
| 06/30/2015 | BIOGEN INC. | BIIB | 60,730 | 50,730 | 24,531,000 | 20,309,000 | $403.94 |
| 03/31/2015 | BIOGEN INC. | BIIB | 10,000 | -30,000 | 4,222,000 | -9,356,000 | $422.20 |
| 12/31/2014 | BIOGEN INC. | BIIB | 40,000 | 40,000 | 13,578,000 | 13,578,000 | $339.45 |
| 09/30/2014 | BIOGEN INC. | BIIB | 0 | -22,000 | 0 | -6,937,000 | |
| 06/30/2014 | BIOGEN INC. | BIIB | 22,000 | 5,000 | 6,937,000 | 1,737,000 | $315.32 |
| 03/31/2014 | BIOGEN INC. | BIIB | 17,000 | 5,000 | 5,200,000 | 1,843,000 | $305.88 |
| 12/31/2013 | BIOGEN INC. | BIIB | 12,000 | 12,000 | 3,357,000 | 3,357,000 | $279.75 |
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