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SPHERA FUNDS MANAGEMENT LTD.
> MRK
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Merck & Co., Inc. | MRK | 120,600 | 0 | 13,916,034,000 | 535,464,000 | $115,390.00 |
| 12/31/2022 | Merck & Co., Inc. | MRK | 120,600 | -246,400 | 13,380,570,000 | 13,348,964,000 | $110,950.00 |
| 09/30/2022 | Merck & Co., Inc. | MRK | 367,000 | 82,000 | 31,606,000 | 5,623,000 | $86.12 |
| 06/30/2022 | Merck & Co., Inc. | MRK | 285,000 | 6,800 | 25,983,000 | 3,157,000 | $91.17 |
| 03/31/2022 | Merck & Co., Inc. | MRK | 278,200 | -68,223 | 22,826,000 | -3,724,000 | $82.05 |
| 12/31/2021 | Merck & Co., Inc. | MRK | 346,423 | 346,423 | 26,550,000 | 26,550,000 | $76.64 |
| 09/30/2021 | Merck & Co., Inc. | MRK | 0 | -772,601 | 0 | -60,085,000 | |
| 06/30/2021 | Merck & Co., Inc. | MRK | 772,601 | 43,793 | 60,085,000 | 469,000 | $77.77 |
| 12/31/2020 | Merck & Co., Inc. | MRK | 728,808 | -155,000 | 59,616,000 | -13,696,000 | $81.80 |
| 09/30/2020 | Merck & Co., Inc. | MRK | 883,808 | 100,000 | 73,312,000 | 12,700,000 | $82.95 |
| 06/30/2020 | Merck & Co., Inc. | MRK | 783,808 | -84,710 | 60,612,000 | -6,212,000 | $77.33 |
| 03/31/2020 | Merck & Co., Inc. | MRK | 868,518 | 313,518 | 66,824,000 | 16,347,000 | $76.94 |
| 12/31/2019 | Merck & Co., Inc. | MRK | 555,000 | 85,000 | 50,477,000 | 10,912,000 | $90.95 |
| 09/30/2019 | Merck & Co., Inc. | MRK | 470,000 | 18,000 | 39,565,000 | 1,665,000 | $84.18 |
| 06/30/2019 | Merck & Co., Inc. | MRK | 452,000 | 75,000 | 37,900,000 | 6,545,000 | $83.85 |
| 03/31/2019 | Merck & Co., Inc. | MRK | 377,000 | -95,000 | 31,355,000 | -4,711,000 | $83.17 |
| 12/31/2018 | Merck & Co., Inc. | MRK | 472,000 | -308,000 | 36,066,000 | -19,267,000 | $76.41 |
| 09/30/2018 | Merck & Co., Inc. | MRK | 780,000 | 100,000 | 55,333,000 | 14,057,000 | $70.94 |
| 06/30/2018 | Merck & Co., Inc. | MRK | 680,000 | 100,000 | 41,276,000 | 9,683,000 | $60.70 |
| 03/31/2018 | Merck & Co., Inc. | MRK | 580,000 | 155,000 | 31,593,000 | 7,678,000 | $54.47 |
| 12/31/2017 | Merck & Co., Inc. | MRK | 425,000 | 0 | 23,915,000 | -3,298,000 | $56.27 |
| 09/30/2017 | Merck & Co., Inc. | MRK | 425,000 | 105,000 | 27,213,000 | 6,704,000 | $64.03 |
| 06/30/2017 | Merck & Co., Inc. | MRK | 320,000 | 25,000 | 20,509,000 | 1,765,000 | $64.09 |
| 03/31/2017 | Merck & Co., Inc. | MRK | 295,000 | -155,000 | 18,744,000 | -7,748,000 | $63.54 |
| 12/31/2016 | Merck & Co., Inc. | MRK | 450,000 | 150,000 | 26,492,000 | 7,769,000 | $58.87 |
| 09/30/2016 | Merck & Co., Inc. | MRK | 300,000 | 200,000 | 18,723,000 | 12,962,000 | $62.41 |
| 06/30/2016 | Merck & Co., Inc. | MRK | 100,000 | 100,000 | 5,761,000 | 5,761,000 | $57.61 |
| 09/30/2015 | Merck & Co., Inc. | MRK | 0 | -400,000 | 0 | -22,772,000 | |
| 06/30/2015 | Merck & Co., Inc. | MRK | 400,000 | 25,000 | 22,772,000 | 1,217,000 | $56.93 |
| 03/31/2015 | Merck & Co., Inc. | MRK | 375,000 | 375,000 | 21,555,000 | 21,555,000 | $57.48 |
| 12/31/2014 | Merck & Co., Inc. | MRK | 0 | -417,530 | 0 | -24,751,000 | |
| 09/30/2014 | Merck & Co., Inc. | MRK | 417,530 | -12,470 | 24,751,000 | -125,000 | $59.28 |
| 06/30/2014 | Merck & Co., Inc. | MRK | 430,000 | -100,000 | 24,876,000 | -5,212,000 | $57.85 |
| 03/31/2014 | Merck & Co., Inc. | MRK | 530,000 | 250,000 | 30,088,000 | 16,074,000 | $56.77 |
| 12/31/2013 | Merck & Co., Inc. | MRK | 280,000 | 280,000 | 14,014,000 | 14,014,000 | $50.05 |
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