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BAKER BROS. ADVISORS LP
> BMRN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2017 | BIOMARIN PHARMACEUTICAL INC | BMRN | 0 | -22,379,000 | 0 | -95,967,000 | |
| 03/31/2017 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | 0 | 95,967,000 | 5,436,000 | $4.29 |
| 12/31/2016 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | 0 | 90,531,000 | -10,874,000 | $4.05 |
| 09/30/2016 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | 0 | 101,405,000 | 16,497,000 | $4.53 |
| 06/30/2016 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | 0 | 84,908,000 | -4,917,000 | $3.79 |
| 03/31/2016 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | 0 | 89,825,000 | -25,333,000 | $4.01 |
| 12/31/2015 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | -519,000 | 115,158,000 | 58,581,000 | $5.15 |
| 09/30/2015 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | -519,000 | 115,619,000 | 59,042,000 | $5.17 |
| 06/30/2015 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | -519,000 | 149,970,000 | 93,393,000 | $6.70 |
| 03/31/2015 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,379,000 | -519,000 | 136,987,000 | 80,410,000 | $6.12 |
| 12/31/2014 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 102,104,000 | 45,527,000 | $4.46 |
| 09/30/2014 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 81,355,000 | 24,778,000 | $3.55 |
| 06/30/2014 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 70,511,000 | 13,934,000 | $3.08 |
| 03/31/2014 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 77,127,000 | 20,550,000 | $3.37 |
| 12/31/2013 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 79,367,000 | 22,790,000 | $3.47 |
| 09/30/2013 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 82,032,000 | 25,455,000 | $3.58 |
| 06/30/2013 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 63,217,000 | 6,640,000 | $2.76 |
| 03/31/2013 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 70,834,000 | 14,257,000 | $3.09 |
| 12/31/2012 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 56,577,000 | 8,880,000 | $2.47 |
| 09/30/2012 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 47,697,000 | 971,000 | $2.08 |
| 06/30/2012 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 0 | 46,726,000 | 5,867,000 | $2.04 |
| 03/31/2012 | BIOMARIN PHARMACEUTICAL INC | BMRN | 22,898,000 | 15,000,000 | 40,859,000 | 26,820,000 | $1.78 |
| 12/31/2011 | BIOMARIN PHARMACEUTICAL INC | BMRN | 7,898,000 | 0 | 14,039,000 | 969,000 | $1.78 |
| 09/30/2011 | BIOMARIN PHARMACEUTICAL INC | BMRN | 7,898,000 | 7,898,000 | 13,070,000 | 13,070,000 | $1.65 |
| 06/30/2011 | BIOMARIN PHARMACEUTICAL INC | BMRN | 0 | -6,410,000 | 0 | -8,748,000 | |
| 03/31/2011 | BIOMARIN PHARMACEUTICAL INC | BMRN | 6,410,000 | 2,500,000 | 8,748,000 | 3,069,000 | $1.36 |
| 12/31/2010 | BIOMARIN PHARMACEUTICAL INC | BMRN | 3,910,000 | 0 | 5,679,000 | 835,000 | $1.45 |
| 09/30/2010 | BIOMARIN PHARMACEUTICAL INC | BMRN | 3,910,000 | 0 | 4,844,000 | 700,000 | $1.24 |
| 06/30/2010 | BIOMARIN PHARMACEUTICAL INC | BMRN | 3,910,000 | 0 | 4,144,000 | -914,000 | $1.06 |
| 03/31/2010 | BIOMARIN PHARMACEUTICAL INC | BMRN | 3,910,000 | -1,090,000 | 5,058,000 | -283,000 | $1.29 |
| 12/31/2009 | BIOMARIN PHARMACEUTICAL INC | BMRN | 5,000,000 | -5,000,000 | 5,341,000 | -5,304,000 | $1.07 |
| 09/30/2009 | BIOMARIN PHARMACEUTICAL INC | BMRN | 10,000,000 | -19,000,000 | 10,645,000 | -15,617,000 | $1.06 |
| 06/30/2009 | BIOMARIN PHARMACEUTICAL INC | BMRN | 29,000,000 | -3,000,000 | 26,262,000 | 8,492,000 | $0.91 |
| 03/31/2009 | BIOMARIN PHARMACEUTICAL INC | BMRN | 32,000,000 | 0 | 17,770,000 | -12,030,000 | $0.56 |
| 12/31/2008 | BIOMARIN PHARMACEUTICAL INC | BMRN | 32,000,000 | 32,000,000 | 29,800,000 | 29,800,000 | $0.93 |
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