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Opaleye Management Inc.
> CMRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | CHIMERIX INC | CMRX | 0 | -365,000 | 0 | -704,000 | |
| 09/30/2022 | CHIMERIX INC | CMRX | 365,000 | -1,065,000 | 704,000 | -2,270,000 | $1.93 |
| 06/30/2022 | CHIMERIX INC | CMRX | 1,430,000 | -4,473,450 | 2,974,000 | -24,064,000 | $2.08 |
| 03/31/2022 | CHIMERIX INC | CMRX | 5,903,450 | 323,450 | 27,038,000 | -8,841,000 | $4.58 |
| 12/31/2021 | CHIMERIX INC | CMRX | 5,580,000 | 950,000 | 35,879,000 | -1,161,000 | $6.43 |
| 06/30/2021 | CHIMERIX INC | CMRX | 4,630,000 | 140,000 | 37,040,000 | -6,244,000 | $8.00 |
| 03/31/2021 | CHIMERIX INC | CMRX | 4,490,000 | 533,500 | 43,284,000 | 24,174,000 | $9.64 |
| 12/31/2020 | CHIMERIX INC | CMRX | 9 | -3,841,491 | 43 | -9,564,957 | $4.83 |
| 09/30/2020 | CHIMERIX INC | CMRX | 3,841,500 | 1,736,500 | 9,565,000 | 3,039,000 | $2.49 |
| 06/30/2020 | CHIMERIX INC | CMRX | 2,105,000 | 2,105,000 | 6,526,000 | 6,526,000 | $3.10 |
| 09/30/2019 | CHIMERIX INC | CMRX | 0 | -1,470,000 | 0 | -6,350,000 | |
| 06/30/2019 | CHIMERIX INC | CMRX | 1,470,000 | 510,000 | 6,350,000 | 4,334,000 | $4.32 |
| 03/31/2019 | CHIMERIX INC | CMRX | 960,000 | -1,060,000 | 2,016,000 | -3,175,000 | $2.10 |
| 12/31/2018 | CHIMERIX INC | CMRX | 2,020,000 | 835,000 | 5,191,000 | 582,000 | $2.57 |
| 09/30/2018 | CHIMERIX INC | CMRX | 1,185,000 | 35,000 | 4,609,000 | -865,000 | $3.89 |
| 06/30/2018 | CHIMERIX INC | CMRX | 1,150,000 | 550,000 | 5,474,000 | 2,354,000 | $4.76 |
| 03/31/2018 | CHIMERIX INC | CMRX | 600,000 | 0 | 3,120,000 | 342,000 | $5.20 |
| 12/31/2017 | CHIMERIX INC | CMRX | 600,000 | -803,000 | 2,778,000 | -4,587,000 | $4.63 |
| 09/30/2017 | CHIMERIX INC | CMRX | 1,403,000 | 123,000 | 7,365,000 | 389,000 | $5.25 |
| 06/30/2017 | CHIMERIX INC | CMRX | 1,280,000 | 65,000 | 6,976,000 | -775,000 | $5.45 |
| 03/31/2017 | CHIMERIX INC | CMRX | 1,215,000 | 45,000 | 7,751,000 | 2,369,000 | $6.38 |
| 12/31/2016 | CHIMERIX INC | CMRX | 1,170,000 | 390,000 | 5,382,000 | 1,061,000 | $4.60 |
| 09/30/2016 | CHIMERIX INC | CMRX | 780,000 | 105,000 | 4,321,000 | 1,668,000 | $5.54 |
| 06/30/2016 | CHIMERIX INC | CMRX | 675,000 | 675,000 | 2,653,000 | 2,653,000 | $3.93 |
| 03/31/2016 | CHIMERIX INC | CMRX | 675,000 | 675,000 | 3,449,000 | 3,449,000 | $5.11 |
| 12/31/2015 | CHIMERIX INC | CMRX | 0 | -310,000 | 0 | -11,842,000 | |
| 09/30/2015 | CHIMERIX INC | CMRX | 310,000 | 310,000 | 11,842,000 | 11,842,000 | $38.20 |
| 06/30/2015 | CHIMERIX INC | CMRX | 440,000 | 440,000 | 20,328,000 | 20,328,000 | $46.20 |
| 03/31/2015 | CHIMERIX INC | CMRX | 565,000 | 565,000 | 21,295,000 | 21,295,000 | $37.69 |
| 12/31/2014 | CHIMERIX INC | CMRX | 805,000 | 805,000 | 32,409,000 | 32,409,000 | $40.26 |
| 09/30/2014 | CHIMERIX INC | CMRX | 755,000 | 755,000 | 20,853,100,000 | 20,853,100,000 | $27,620.00 |
| 06/30/2014 | CHIMERIX INC | CMRX | 790,000 | 790,000 | 17,333,000 | 17,333,000 | $21.94 |
| 03/31/2014 | CHIMERIX INC | CMRX | 536,000 | 536,000 | 12,242,000 | 12,242,000 | $22.84 |
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