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BAKER BROS. ADVISORS LP
> NVTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Invitae Corp | NVTA | 8,881,104 | 479,069 | 10,035,648,000 | -5,592,137,000 | $1,130.00 |
| 12/31/2022 | Invitae Corp | NVTA | 8,402,035 | 0 | 15,627,785,000 | 15,607,116,000 | $1,860.00 |
| 09/30/2022 | Invitae Corp | NVTA | 8,402,035 | -1,471,453 | 20,669,000 | -3,422,000 | $2.46 |
| 06/30/2022 | Invitae Corp | NVTA | 9,873,488 | 0 | 24,091,000 | -54,601,000 | $2.44 |
| 03/31/2022 | Invitae Corp | NVTA | 9,873,488 | 0 | 78,692,000 | -72,076,000 | $7.97 |
| 12/31/2021 | Invitae Corp | NVTA | 9,873,488 | 0 | 150,768,162 | -129,934,838 | $15.27 |
| 09/30/2021 | Invitae Corp | NVTA | 9,873,488 | -375,087 | 280,703,000 | -64,981,000 | $28.43 |
| 06/30/2021 | Invitae Corp | NVTA | 10,248,575 | -5,500,607 | 345,684,000 | -256,092,000 | $33.73 |
| 03/31/2021 | Invitae Corp | NVTA | 15,749,182 | 100,000 | 601,776,000 | -52,516,000 | $38.21 |
| 12/31/2020 | Invitae Corp | NVTA | 15,774,095 | 3,923,133 | 659,514,912 | 145,775,912 | $41.81 |
| 09/30/2020 | Invitae Corp | NVTA | 11,850,962 | 0 | 513,739,000 | 154,773,000 | $43.35 |
| 06/30/2020 | Invitae Corp | NVTA | 11,850,962 | 2,750,347 | 358,966,000 | 234,561,000 | $30.29 |
| 03/31/2020 | Invitae Corp | NVTA | 9,100,615 | 3,450 | 124,405,000 | -22,332,000 | $13.67 |
| 12/31/2019 | Invitae Corp | NVTA | 9,222,078 | 429,400 | 148,752,118 | -20,682,882 | $16.13 |
| 09/30/2019 | Invitae Corp | NVTA | 8,792,678 | 4,890,257 | 169,435,000 | 77,728,000 | $19.27 |
| 06/30/2019 | Invitae Corp | NVTA | 3,902,421 | 0 | 91,707,000 | 312,000 | $23.50 |
| 03/31/2019 | Invitae Corp | NVTA | 3,902,421 | 0 | 91,395,000 | 48,234,000 | $23.42 |
| 01/31/2019 | Invitae Corp | NVTA | 4,885,553 | -3,513,858 | 68,788,586 | -71,733,414 | $14.08 |
| 12/31/2018 | Invitae Corp | NVTA | 3,902,421 | -4,496,990 | 43,161,000 | -97,361,000 | $11.06 |
| 09/30/2018 | Invitae Corp | NVTA | 8,399,411 | 0 | 140,522,000 | 78,786,000 | $16.73 |
| 06/30/2018 | Invitae Corp | NVTA | 8,399,411 | 1,111,111 | 61,736,000 | -4,442,000 | $7.35 |
| 12/31/2017 | Invitae Corp | NVTA | 7,288,300 | 0 | 66,178,000 | -2,114,000 | $9.08 |
| 09/30/2017 | Invitae Corp | NVTA | 7,288,300 | 0 | 68,292,000 | -1,384,000 | $9.37 |
| 07/31/2017 | Invitae Corp | NVTA | 7,288,300 | 0 | 67,635,424 | -2,040,576 | $9.28 |
| 06/30/2017 | Invitae Corp | NVTA | 7,288,300 | 0 | 69,676,000 | -10,933,000 | $9.56 |
| 03/31/2017 | Invitae Corp | NVTA | 7,288,300 | 0 | 80,609,000 | 22,740,000 | $11.06 |
| 12/31/2016 | Invitae Corp | NVTA | 7,288,300 | 733,333 | 57,869,000 | 447,000 | $7.94 |
| 09/30/2016 | Invitae Corp | NVTA | 6,554,967 | 0 | 57,422,000 | 8,981,000 | $8.76 |
| 06/30/2016 | Invitae Corp | NVTA | 6,554,967 | 0 | 48,441,000 | -18,616,000 | $7.39 |
| 03/31/2016 | Invitae Corp | NVTA | 6,554,967 | 0 | 67,057,000 | 13,241,000 | $10.23 |
| 12/31/2015 | Invitae Corp | NVTA | 6,554,967 | 6,554,967 | 53,816,000 | 53,816,000 | $8.21 |
| 09/30/2015 | Invitae Corp | NVTA | 6,554,967 | 6,554,967 | 47,327,000 | 47,327,000 | $7.22 |
| 06/30/2015 | Invitae Corp | NVTA | 6,554,967 | 6,554,967 | 97,538,000 | 97,538,000 | $14.88 |
| 03/31/2015 | Invitae Corp | NVTA | 6,554,967 | 6,554,967 | 109,861,000 | 109,861,000 | $16.76 |
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