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Rock Springs Capital Management LP
> ALNY
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 345,000 | 0 | 65,529,300,000 | -3,581,100,000 | $189,940.00 |
| 03/31/2023 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 345,000 | 12,500 | 69,110,400,000 | -9,908,225,000 | $200,320.00 |
| 12/31/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 332,500 | 0 | 79,018,625,000 | 78,952,072,000 | $237,650.00 |
| 09/30/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 332,500 | 0 | 66,553,000 | 18,058,000 | $200.16 |
| 06/30/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 332,500 | 0 | 48,495,000 | -5,799,000 | $145.85 |
| 03/31/2022 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 332,500 | 0 | 54,294,000 | -2,091,000 | $163.29 |
| 12/31/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 332,500 | 21,500 | 56,385,000 | -2,335,000 | $169.58 |
| 09/30/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 311,000 | 11,000 | 58,720,000 | 7,864,000 | $188.81 |
| 06/30/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 300,000 | 0 | 50,856,000 | 8,499,000 | $169.52 |
| 03/31/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 300,000 | -35,000 | 42,357,000 | -1,183,000 | $141.19 |
| 12/31/2020 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 335,000 | -4,814 | 43,540,000 | -5,937,000 | $129.97 |
| 09/30/2020 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 339,814 | -5,186 | 49,477,000 | -1,621,000 | $145.60 |
| 06/30/2020 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 345,000 | -36,500 | 51,098,000 | 9,572,000 | $148.11 |
| 03/31/2020 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 381,500 | 17,500 | 41,526,000 | -396,000 | $108.85 |
| 12/31/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 364,000 | 33,500 | 41,922,000 | 15,343,000 | $115.17 |
| 09/30/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 330,500 | 2,800 | 26,579,000 | 2,801,000 | $80.42 |
| 06/30/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 327,700 | 94,200 | 23,778,000 | 1,957,000 | $72.56 |
| 03/31/2019 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 233,500 | 39,500 | 21,821,000 | 7,676,000 | $93.45 |
| 12/31/2018 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 194,000 | -2,500 | 14,145,000 | -3,053,000 | $72.91 |
| 09/30/2018 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 196,500 | 23,000 | 17,198,000 | 110,000 | $87.52 |
| 06/30/2018 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 173,500 | 30,500 | 17,088,000 | 57,000 | $98.49 |
| 03/31/2018 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 143,000 | 13,000 | 17,031,000 | 514,000 | $119.10 |
| 12/31/2017 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 130,000 | 25,000 | 16,517,000 | 4,181,000 | $127.05 |
| 09/30/2017 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 105,000 | 0 | 12,336,000 | 3,961,000 | $117.49 |
| 06/30/2017 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | 105,000 | 105,000 | 8,375,000 | 8,375,000 | $79.76 |
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