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Rock Springs Capital Management LP
> AGIO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,686,167 | 24,562 | 76,072,249,000 | 14,935,182,000 | $28,320.00 |
| 03/31/2023 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,661,605 | -334,987 | 61,137,067,000 | -23,007,236,000 | $22,970.00 |
| 12/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,996,592 | -61,277 | 84,144,303,000 | 84,057,826,000 | $28,080.00 |
| 09/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 3,057,869 | 129,411 | 86,477,000 | 21,553,000 | $28.28 |
| 06/30/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,928,458 | 263,183 | 64,924,000 | -12,662,000 | $22.17 |
| 03/31/2022 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,665,275 | 18,650 | 77,586,000 | -9,409,000 | $29.11 |
| 12/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,646,625 | 90,446 | 86,995,000 | -30,973,000 | $32.87 |
| 09/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,556,179 | -18,129 | 117,968,000 | -23,902,000 | $46.15 |
| 06/30/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,574,308 | 30,708 | 141,870,000 | 10,518,000 | $55.11 |
| 03/31/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,543,600 | 20,079 | 131,352,000 | 22,008,000 | $51.64 |
| 12/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 2,523,521 | 942,012 | 109,344,000 | 53,991,000 | $43.33 |
| 09/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,581,509 | 401,789 | 55,353,000 | -7,738,000 | $35.00 |
| 06/30/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,179,720 | 124,220 | 63,091,000 | 25,642,000 | $53.48 |
| 03/31/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | 1,055,500 | 414,000 | 37,449,000 | 6,817,000 | $35.48 |
| 12/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 641,500 | 289,000 | 30,632,000 | 19,211,000 | $47.75 |
| 09/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 352,500 | 182,000 | 11,421,000 | 2,916,000 | $32.40 |
| 06/30/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 170,500 | 53,000 | 8,505,000 | 581,000 | $49.88 |
| 03/31/2019 | AGIOS PHARMACEUTICALS, INC. | AGIO | 117,500 | 117,500 | 7,924,000 | 7,924,000 | $67.44 |
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