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Tekla Capital Management LLC
> AMGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AMGEN INC | AMGN | 616,539 | 60,600 | 136,883,989,000 | 2,485,736,000 | $222,020.00 |
| 03/31/2023 | AMGEN INC | AMGN | 555,939 | 37,070 | 134,398,253,000 | 134,281,300,000 | $241,750.00 |
| 09/30/2022 | AMGEN INC | AMGN | 518,869 | -29,549 | 116,953,000 | -16,477,000 | $225.40 |
| 06/30/2022 | AMGEN INC | AMGN | 548,418 | -26,500 | 133,430,000 | -5,597,000 | $243.30 |
| 03/31/2022 | AMGEN INC | AMGN | 574,918 | 0 | 139,027,000 | 9,688,000 | $241.82 |
| 12/31/2021 | AMGEN INC | AMGN | 574,918 | 0 | 129,339,000 | 7,083,000 | $224.97 |
| 09/30/2021 | AMGEN INC | AMGN | 574,918 | 111,513 | 122,256,000 | 9,301,000 | $212.65 |
| 06/30/2021 | AMGEN INC | AMGN | 463,405 | 46,845 | 112,955,000 | 9,311,000 | $243.75 |
| 03/31/2021 | AMGEN INC | AMGN | 416,560 | 0 | 103,644,000 | 7,869,000 | $248.81 |
| 12/31/2020 | AMGEN INC | AMGN | 416,560 | -191,658 | 95,775,000 | -58,810,000 | $229.92 |
| 09/30/2020 | AMGEN INC | AMGN | 608,218 | -3,744 | 154,585,000 | 10,248,000 | $254.16 |
| 06/30/2020 | AMGEN INC | AMGN | 611,962 | 12,091 | 144,337,000 | 22,725,000 | $235.86 |
| 03/31/2020 | AMGEN INC | AMGN | 599,871 | -17,556 | 121,612,000 | -27,231,000 | $202.73 |
| 12/31/2019 | AMGEN INC | AMGN | 617,427 | -14,860 | 148,843,000 | 26,489,000 | $241.07 |
| 09/30/2019 | AMGEN INC | AMGN | 632,287 | -97,371 | 122,354,000 | -12,107,000 | $193.51 |
| 06/30/2019 | AMGEN INC | AMGN | 729,658 | 25,275 | 134,461,000 | 642,000 | $184.28 |
| 03/31/2019 | AMGEN INC | AMGN | 704,383 | 26,528 | 133,819,000 | 1,861,000 | $189.98 |
| 12/31/2018 | AMGEN INC | AMGN | 677,855 | 0 | 131,958,000 | -8,555,000 | $194.67 |
| 09/30/2018 | AMGEN INC | AMGN | 677,855 | -22,733 | 140,513,000 | 11,191,000 | $207.29 |
| 06/30/2018 | AMGEN INC | AMGN | 700,588 | 0 | 129,322,000 | 9,886,000 | $184.59 |
| 03/31/2018 | AMGEN INC | AMGN | 700,588 | -161,586 | 119,436,000 | -30,496,000 | $170.48 |
| 12/31/2017 | AMGEN INC | AMGN | 862,174 | 241,900 | 149,932,000 | 34,282,000 | $173.90 |
| 09/30/2017 | AMGEN INC | AMGN | 620,274 | -64,550 | 115,650,000 | -2,297,000 | $186.45 |
| 06/30/2017 | AMGEN INC | AMGN | 684,824 | 0 | 117,947,000 | 5,588,000 | $172.23 |
| 03/31/2017 | AMGEN INC | AMGN | 684,824 | 363,184 | 112,359,000 | 65,332,000 | $164.07 |
| 12/31/2016 | AMGEN INC | AMGN | 321,640 | 0 | 47,027,000 | -6,626,000 | $146.21 |
| 09/30/2016 | AMGEN INC | AMGN | 321,640 | 0 | 53,653,000 | 1,441,000 | $166.81 |
| 06/30/2016 | AMGEN INC | AMGN | 331,740 | 10,100 | 50,474,000 | 2,251,000 | $152.15 |
| 03/31/2016 | AMGEN INC | AMGN | 321,640 | 0 | 48,223,000 | -3,989,000 | $149.93 |
| 12/31/2015 | AMGEN INC | AMGN | 321,640 | -188,402 | 52,212,000 | -19,428,000 | $162.33 |
| 09/30/2015 | AMGEN INC | AMGN | 321,640 | -188,402 | 44,489,000 | -27,151,000 | $138.32 |
| 06/30/2015 | AMGEN INC | AMGN | 497,280 | -12,762 | 76,342,000 | 4,702,000 | $153.52 |
| 03/31/2015 | AMGEN INC | AMGN | 351,779 | -158,263 | 56,232,000 | -15,408,000 | $159.85 |
| 12/31/2014 | AMGEN INC | AMGN | 380,279 | -129,763 | 60,575,000 | -11,065,000 | $159.29 |
| 09/30/2014 | AMGEN INC | AMGN | 510,042 | 510,042 | 71,640,000 | 71,640,000 | $140.46 |
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