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Tekla Capital Management LLC
> TMO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 98,987 | 5,282 | 51,646,467,000 | -2,362,284,000 | $521,750.00 |
| 03/31/2023 | THERMO FISHER SCIENTIFIC INC. | TMO | 93,705 | 0 | 54,008,751,000 | 53,961,225,000 | $576,370.00 |
| 09/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 93,705 | -3,900 | 47,526,000 | -5,501,000 | $507.19 |
| 06/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 97,605 | 0 | 53,027,000 | -4,623,000 | $543.28 |
| 03/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 97,605 | -54,721 | 57,650,000 | -43,988,000 | $590.65 |
| 12/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 152,326 | 6,210 | 101,638,000 | 18,158,000 | $667.24 |
| 09/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 146,116 | 5,986 | 83,480,000 | 12,789,000 | $571.33 |
| 06/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 140,130 | 26,477 | 70,691,000 | 18,822,000 | $504.47 |
| 03/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 113,653 | -13,900 | 51,869,000 | -7,543,000 | $456.38 |
| 12/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 127,553 | 98,092 | 59,412,000 | 46,404,000 | $465.78 |
| 09/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 29,461 | -76,564 | 13,008,000 | -25,409,000 | $441.53 |
| 06/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 106,025 | -6,000 | 38,417,000 | 6,647,000 | $362.34 |
| 03/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 112,025 | -11,383 | 31,770,000 | -8,322,000 | $283.60 |
| 12/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 123,408 | 34,098 | 40,092,000 | 14,079,000 | $324.87 |
| 09/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 89,310 | -46,888 | 26,013,000 | -13,986,000 | $291.27 |
| 06/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 136,198 | -6,545 | 39,999,000 | 927,000 | $293.68 |
| 03/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 142,743 | -49,152 | 39,072,000 | -3,872,000 | $273.72 |
| 12/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 191,895 | 11,500 | 42,944,000 | -1,087,000 | $223.79 |
| 09/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 180,395 | 27,700 | 44,031,000 | 12,402,000 | $244.08 |
| 06/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 152,695 | 4,840 | 31,629,000 | 1,103,000 | $207.14 |
| 03/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 147,855 | 9,887 | 30,526,000 | 4,329,000 | $206.46 |
| 12/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 137,968 | -81,104 | 26,197,000 | -15,251,000 | $189.88 |
| 09/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 219,072 | 79,952 | 41,448,000 | 17,176,000 | $189.20 |
| 06/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 139,120 | -88,900 | 24,272,000 | -10,752,000 | $174.47 |
| 03/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 228,020 | 86,900 | 35,024,000 | 15,112,000 | $153.60 |
| 12/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 141,120 | 54,725 | 19,912,000 | 6,170,000 | $141.10 |
| 09/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | 0 | 13,742,000 | 1,487,000 | $159.06 |
| 06/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | 0 | 12,766,000 | 533,000 | $147.76 |
| 03/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | 0 | 12,233,000 | -22,000 | $141.59 |
| 12/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | -180,480 | 12,255,000 | -20,224,000 | $141.85 |
| 09/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | -180,480 | 10,564,000 | -21,915,000 | $122.28 |
| 06/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 86,395 | -180,480 | 11,211,000 | -21,268,000 | $129.76 |
| 03/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 141,695 | -125,180 | 19,035,000 | -13,444,000 | $134.34 |
| 12/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 120,995 | -145,880 | 15,159,000 | -17,320,000 | $125.29 |
| 09/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 266,875 | 266,875 | 32,479,000 | 32,479,000 | $121.70 |
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