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Palo Alto Investors LP
> PRTA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,657,458 | -6,319 | 113,171,232,000 | 32,527,961,000 | $68,280.00 |
| 03/31/2023 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,663,777 | 5,200 | 80,643,271,000 | -19,285,993,000 | $48,470.00 |
| 12/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,658,577 | 8,800 | 99,929,264,000 | 99,829,238,000 | $60,250.00 |
| 09/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,649,777 | -31,700 | 100,026,000 | 54,374,000 | $60.63 |
| 06/30/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,681,477 | 0 | 45,652,000 | -15,840,000 | $27.15 |
| 03/31/2022 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,681,477 | -3,805 | 61,492,000 | -21,761,000 | $36.57 |
| 12/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,685,282 | 0 | 83,253,000 | -36,790,000 | $49.40 |
| 09/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,685,282 | -46,200 | 120,043,000 | 31,028,000 | $71.23 |
| 06/30/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,731,482 | -11,023 | 89,015,000 | 45,243,000 | $51.41 |
| 03/31/2021 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,742,505 | 50,700 | 43,772,000 | 23,453,000 | $25.12 |
| 12/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,691,805 | 363,071 | 20,319,000 | 7,045,000 | $12.01 |
| 09/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,328,734 | 557,669 | 13,274,000 | 5,209,000 | $9.99 |
| 06/30/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 771,065 | -4,231 | 8,065,000 | -231,000 | $10.46 |
| 03/31/2020 | PROTHENA CORP PUBLIC LTD CO | PRTA | 775,296 | -217,453 | 8,296,000 | -7,419,000 | $10.70 |
| 12/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 992,749 | -11,700 | 15,715,000 | 7,840,000 | $15.83 |
| 09/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,004,449 | -104,061 | 7,875,000 | -3,842,000 | $7.84 |
| 06/30/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,108,510 | 0 | 11,717,000 | -1,729,000 | $10.57 |
| 03/31/2019 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,108,510 | 0 | 13,446,000 | 2,028,000 | $12.13 |
| 12/31/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,108,510 | 5,185 | 11,418,000 | -3,013,000 | $10.30 |
| 09/30/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,103,325 | 0 | 14,431,000 | -1,655,000 | $13.08 |
| 06/30/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,103,325 | 1,987 | 16,086,000 | -24,344,000 | $14.58 |
| 03/31/2018 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,101,338 | 5,683 | 40,430,000 | -646,000 | $36.71 |
| 12/31/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,095,655 | 0 | 41,076,000 | -29,890,000 | $37.49 |
| 09/30/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,095,655 | 21,700 | 70,966,000 | 12,844,000 | $64.77 |
| 06/30/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,073,955 | 18,100 | 58,122,000 | -784,000 | $54.12 |
| 03/31/2017 | PROTHENA CORP PUBLIC LTD CO | PRTA | 1,055,855 | 62,000 | 58,906,000 | 10,018,000 | $55.79 |
| 12/31/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 993,855 | 59,400 | 48,888,000 | -7,151,000 | $49.19 |
| 09/30/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 934,455 | 145,837 | 56,039,000 | 28,469,000 | $59.97 |
| 06/30/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 788,618 | 788,618 | 27,570,000 | 27,570,000 | $34.96 |
| 03/31/2016 | PROTHENA CORP PUBLIC LTD CO | PRTA | 695,518 | 0 | 28,628,000 | -18,744,000 | $41.16 |
| 12/31/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 695,518 | 695,518 | 47,372,000 | 47,372,000 | $68.11 |
| 09/30/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 695,918 | 695,918 | 31,553,000 | 31,553,000 | $45.34 |
| 06/30/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 695,918 | 695,918 | 36,654,000 | 36,654,000 | $52.67 |
| 03/31/2015 | PROTHENA CORP PUBLIC LTD CO | PRTA | 695,918 | 695,918 | 26,542,000 | 26,542,000 | $38.14 |
| 12/31/2014 | PROTHENA CORP PUBLIC LTD CO | PRTA | 691,218 | 691,218 | 14,350,000 | 14,350,000 | $20.76 |
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